| Gene Symbol |
INPP5A
|
| Entrez Gene |
3632
|
| Alt Symbol |
5PTASE
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
inositol polyphosphate-5-phosphatase, 40kDa
|
| Other Description |
43 kDa inositol polyphosphate 5-phophatase|CTCL tumor antigen HD-CL-02|InsP3 5-phosphatase|inositol polyphosphate-5-phosphatase, 40kD|inositol trisphosphate-5-phosphatase, 40kD|type I inositol 1,4,5-trisphosphate 5-phosphatase|type I inositol-1,4,5-trisphosphate 5-phophatase|type I inositol-1,4,5-trisphosphate 5-phosphatase
|
| Swissprots |
Q14642 Q14640 Q5JSF1 D3DXI3
|
| Accessions |
AAK13252 EAW61306 EAW61307 Q14642 AF273055 AAM44458 BC052265 AAH52265 BC062300 AAH62300 BC096280 AAH96280 BC096281 AAH96281 BC117515 AAI17516 BM467443 BM666428 CB960907 X77567 CAA54676 Z31695 CAA83500 XM_011539768 XP_011538070 XR_945735 NM_005539 NP_005530
|
| Function |
Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction.
|
| Subcellular Location |
Membrane; Lipid-anchor.
|
| Tissue Specificity |
Brain; high level in Purkinje cells.
|
| Top Pathways |
Inositol phosphate metabolism, Phosphatidylinositol signaling system
|