POLE

Gene Symbol POLE
Entrez Gene 5426
Alt Symbol CRCS12, FILS, POLE1
Species Human
Gene Type protein-coding
Description polymerase (DNA directed), epsilon, catalytic subunit
Other Description DNA polymerase II subunit A|DNA polymerase epsilon catalytic subunit A
Swissprots Q07864 Q13533 Q86VH9
Accessions AAD44690 AAD44691 AAD44692 AAO46109 AAP12650 CBX47649 EAW54830 EAW54831 EAW54832 EAW54833 EAW54834 Q07864 AF128542 AAD45663 AF128544 AK025087 BAB15063 AK093003 BAG52636 AK128248 AL080203 CAB45774 BC007599 AAH07599 BC011376 BC021559 AAH21559 BC087613 AAH87613 BC144561 BC172436 AAI72436 BX647647 CX782956 L09561 AAC19148 S60080 AAA15448 U49356 AAA90924 XM_011534795 XP_011533097 XM_011534796 XP_011533098 XM_011534797 XP_011533099 XM_011534798 XP_011533100 XM_011534799 XP_011533101 XM_011534800 XP_011533102 XM_011534801 XP_011533103 XM_011534802 XP_011533104 XR_941395 NM_006231 NP_006222
Function Participates in DNA repair and in chromosomal DNA replication.
Subcellular Location Nucleus.
Top Pathways DNA replication, Base excision repair, Nucleotide excision repair, HTLV-I infection, Purine metabolism

DNA pol ε (0.N.250) - sc-70975 from Santa Cruz Biotechnology

Host Mouse
Clonality Monoclonal
DNA pol ε (0.N.250): sc-70975. Western blot analysis of DNA pol ε expression in Jurkat (A) and K-562 (B) nuclear extracts.

DNA pol ε (93H3A) - sc-56655 from Santa Cruz Biotechnology

Host Mouse
Clonality Monoclonal
DNA pol ε (93H3A): sc-56655. Western blot analysis of DNA pol ε expression in Jurkat (A) and K-562 (B) nuclear extracts.

DNA pol ε A (34) - sc-135885 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
DNA pol ε A (34): sc-135885. Western blot analysis of DNA pol ε A expression in HeLa whole cell lysate.

DNA pol ε A (3C5.1) - sc-12728 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DNA pol ε A (3C5.1): sc-12728. Western blot analysis of DNA pol ε A expression in Jurkat (A), K-562 (B) and HeLa (C) nuclear extracts.

DNA pol ε A (N-19) - sc-8802 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-POLE antibody - ab110876 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab110876, at a 1/50 dilution, staining POLE in paraffin embedded Human breast carcinoma tissue by Immunohistochemistry, in the absence (left panel) or presence (right panel) of the immunizing peptide.

Anti-POLE antibody - ab67420 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-POLE antibody (ab67420) at 1/500 dilutionLane 1 : POLE transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg/ml per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-POLE antibody - ab172081 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-POLE antibody (ab172081) at 1 µg/mlLane 1 : POLE-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L) at 1/7500 dilutiondeveloped using the ECL technique

Anti-POLE antibody [93H3A] - ab140248 from Abcam

Prices $370.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone 93H3A

Anti-POLE antibody [EPR6299] - ab134941 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6299
All lanes : Anti-POLE antibody [EPR6299] (ab134941) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : K562 cell lysateLane 3 : 293T cell lysateLane 4 : Jurkat cell lysateLysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilutiondeveloped using the ECL technique

Anti-POLE antibody [EPR6300] - ab128877 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6300
All lanes : Anti-POLE antibody [EPR6300] (ab128877) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : HeLa cell lysate Lane 3 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-POLE / POLE1 Antibody (C-Terminus, clone EPR6300) - LS-C152424 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6300
Western blot analysis on (A) K562, (B) HeLa, and (C) 293T cell lysates using anti-POLE antibody.

Anti-POLE / POLE1 Antibody (Internal, clone EPR6299) IHC-plus™ - LS-B8695 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6299
Anti-POLE / POLE1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-POLE / POLE1 Antibody (aa1-176) - LS-C22848 from LifeSpan Bioscience

Prices $530.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal

Anti-POLE / POLE1 Antibody (aa1-371) - LS-C131531 from LifeSpan Bioscience

Prices $445.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-POLE / POLE1 Antibody (clone 93H3A) - LS-C88249 from LifeSpan Bioscience

Prices $280.00, $555.00, $830.00
Sizes 20 µg, 100 µg, 1 ml
Host Mouse
Clonality Monoclonal
Clone 93H3A

Anti-POLE / POLE1 Antibody (clone 93H3A, Azide-free) - LS-C88251 from LifeSpan Bioscience

Prices $620.00, $885.00
Sizes 100 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone 93H3A

Anti-POLE / POLE1 Antibody (clone 93H3A, Biotin) - LS-C88250 from LifeSpan Bioscience

Prices $325.00, $730.00, $1,070.00
Sizes 20 µg, 100 µg, 1 ml
Host Mouse
Clonality Monoclonal
Clone 93H3A

Anti-POLE / POLE1 Antibody (aa1261-1310) - LS-C119909 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma tissue, using POLE1 Antibody. The picture on the right is treated with the synthesized peptide.

DNA Polymerase epsilon catalytic subunit A Antibody - NBP1-68470 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: POLE Antibody [NBP1-68470] - Analysis of HepG2 cells.

DNA Polymerase epsilon catalytic subunit A Antibody - H00005426-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: POLE Antibody [H00005426-B01] - analysis of POLE expression in transfected 293T cell line by POLE MaxPab polyclonal antibody (B01). Lane 1: POLE transfected lysate (40.81 KDa). Lane 2: Non-transfected lysate.

DNA Polymerase epsilon catalytic subunit A Antibody - H00005426-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: DNA Polymerase epsilon catalytic subunit A Antibody [H00005426-B01P] - Analysis of POLE expression in transfected 293T cell line by POLE polyclonal antibody. Lane 1: POLE transfected lysate(40.81 KDa). Lane 2: Non-transfected lysate.

DNA Polymerase epsilon catalytic subunit A Antibody - H00005426-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DNA Polymerase epsilon catalytic subunit A Antibody [H00005426-D01P] - Analysis of POLE expression in transfected 293T cell line by POLE polyclonal antibody.Lane 1: POLE transfected lysate(41.50 KDa).Lane 2: Non-transfected lysate.

Anti-POLE antibody produced in mouse - SAB1400219 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Polyclonal Anti-POLE, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400219</B>: Antibody concentration: 1.0 μg/mL using HeLa cells.

Anti-POLE1 antibody produced in rabbit - SAB4502238 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-POLE1: <B>Cat. No. SAB4502238</B>: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-POLE1 antibody. Cells on the left were treated with the Anti-POLE1 antibody. Cells on the right (negative control) were treated with both Anti-POLE1 antibody and the synthesized immunogen peptide.
Search more