Gene Symbol | POLE |
---|---|
Entrez Gene | 5426 |
Alt Symbol | CRCS12, FILS, POLE1 |
Species | Human |
Gene Type | protein-coding |
Description | polymerase (DNA directed), epsilon, catalytic subunit |
Other Description | DNA polymerase II subunit A|DNA polymerase epsilon catalytic subunit A |
Swissprots | Q07864 Q13533 Q86VH9 |
Accessions | AAD44690 AAD44691 AAD44692 AAO46109 AAP12650 CBX47649 EAW54830 EAW54831 EAW54832 EAW54833 EAW54834 Q07864 AF128542 AAD45663 AF128544 AK025087 BAB15063 AK093003 BAG52636 AK128248 AL080203 CAB45774 BC007599 AAH07599 BC011376 BC021559 AAH21559 BC087613 AAH87613 BC144561 BC172436 AAI72436 BX647647 CX782956 L09561 AAC19148 S60080 AAA15448 U49356 AAA90924 XM_011534795 XP_011533097 XM_011534796 XP_011533098 XM_011534797 XP_011533099 XM_011534798 XP_011533100 XM_011534799 XP_011533101 XM_011534800 XP_011533102 XM_011534801 XP_011533103 XM_011534802 XP_011533104 XR_941395 NM_006231 NP_006222 |
Function | Participates in DNA repair and in chromosomal DNA replication. |
Subcellular Location | Nucleus. |
Top Pathways | DNA replication, Base excision repair, Nucleotide excision repair, HTLV-I infection, Purine metabolism |
DNA pol ε A siRNA (h) - sc-43728 from Santa Cruz Biotechnology
|
||||||||
DNA pol ε A shRNA Plasmid (h) - sc-43728-SH from Santa Cruz Biotechnology
|
||||||||
DNA pol ε A shRNA (h) Lentiviral Particles - sc-43728-V from Santa Cruz Biotechnology
|
||||||||
DNA Polymerase epsilon catalytic subunit A RNAi - H00005426-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU140421 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN17094 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17094 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR07237 from Sigma-Aldrich
|
||||||||
POLE siRNA (Human) - CRH3629 from Cohesion Biosciences
|
||||||||
shRNA set against Human POLE (NM_006231.2) - SHH379164 from Creative biogene
|
||||||||
shRNA set against Human POLE(NM_006231.2) - SHR126510 from Creative biogene
|
||||||||
Human POLE siRNA - orb264131 from Biorbyt
|
||||||||
POLE shRNA Plasmid (Human) - CHH3629 from Cohesion Biosciences
|
||||||||
POLE miRNA 3'UTR clone - MiUTR1H-08065 from Creative biogene
|