TACC3

Gene Symbol TACC3
Entrez Gene 10460
Alt Symbol ERIC-1, ERIC1
Species Human
Gene Type protein-coding
Description transforming, acidic coiled-coil containing protein 3
Other Description transforming acidic coiled-coil-containing protein 3
Swissprots Q3KQS5 Q2NKK4 Q9Y6A5 Q9UMQ1
Accessions EAW82574 EAW82575 Q9Y6A5 AA682436 AF093543 AAD25964 AF479620 AAN76993 AI684124 AJ243997 CAB53009 AK225631 AK302463 BAG63753 AK304579 BAG65367 AK310660 BC106071 AAI06072 BC111771 AAI11772 DB098941 U38441 XM_005247929 XP_005247986 XM_005247930 XP_005247987 XM_011513386 XP_011511688 XM_011513387 XP_011511689 NM_006342 NP_006333
Function Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May be involved in the control of cell growth and differentiation. May contribute to cancer. {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways RNA transport

Phospho-TACC3 (Ser558) (D8H10) XP ® Rabbit mAb - 8842 from Cell Signaling Technology

Prices $119.00, $318.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D8H10
Western blot analysis of extracts from HT-29 cells, untreated (-) or synchronized in mitosis by thymidine block (2 mM, 17 hr) followed by nocodozole treatment (100 ng/ml, 24 hr) (+), using Phospho-TACC3 (Ser558) (D8H10) XP ® Rabbit mAb.

Phospho-TACC3 (Ser558) Antibody - 5645 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HT-29 and U-2 OS cells, untreated or synchronized in mitosis by thymidine block (2 mM, 16 hours) followed by nocodozole treatment (100 ng/ml, 24 hours), using Phospho-TACC3 (Ser558) Antibody.

TACC3 (D9E4) XP ® Rabbit mAb - 8069 from Cell Signaling Technology

Prices $277.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D9E4
Western blot analysis of extracts from various cell lines using TACC3 (D9E4) XP ® Rabbit mAb.

TACC3 (C-5) - sc-271165 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TACC3 (C-5): sc-271165. Immunoperoxidase staining of formalin fixed, paraffin-embedded human tonsil tissue showing cytoplasmic staining of cells in germinal and non-germinal centers.

TACC3 (D-17) - sc-5884 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TACC3 (D-17): sc-5884. Western blot analysis of TACC3 expression in non-transfected: sc-117752 (A) and human TACC3 transfected: sc-111721 (B) 293T whole cell lysates.

TACC3 (C-2) - sc-376883 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TACC3 (C-2): sc-376883. Western blot analysis of TACC3 expression in Jurkat whole cell lysate.

TACC3 (D-2) - sc-48368 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TACC3 (D-2): sc-48368. Immunoperoxidase staining of formalin fixed, paraffin-embedded human tonsil tissue showing cytoplasmic staining of follicle cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

TACC3 (F-11) - sc-376839 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TACC3 (F-11): sc-376839. Western blot analysis of TACC3 expression in Jurkat whole cell lysate.

TACC3 (E-4) - sc-376900 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TACC3 (E-4): sc-376900. Western blot analysis of TACC3 expression in Jurkat whole cell lysate.

TACC3 (H-300) - sc-22773 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TACC3 (H-300): sc-22773. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

TACC3 (S-18) - sc-5887 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TACC3 (S-18): sc-5887. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

TACC3 (T-17) - sc-5885 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TACC3 (T-17): sc-5885. Western blot analysis of TACC3 expression in non-transfected: sc-117752 (A) and human TACC3 transfected: sc-111721 (B) 293T whole cell lysates.

Anti-TACC3 antibody - ab56595 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
TACC3 antibody (ab56595) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.

Anti-TACC3 antibody - ab138262 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TACC3 antibody (ab138262) at 1/500 dilution + HepG2 cell lysate at 30 µg

Anti-TACC3 antibody [1E8] - ab118985 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E8
All lanes : Anti-TACC3 antibody [1E8] (ab118985) at 1/1000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control cDNALane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY TACC3 cDNALysates/proteins at 5 µg per lane.

Anti-TACC3 antibody [EPR7756] - ab134154 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7756
Anti-TACC3 antibody [EPR7756] (ab134154) at 1/2000 dilution (purified) + HeLa cell lysate at 20 µgSecondaryPeroxidase-conjugated goat anti-rabbit IgG (H+L) at 1/1000 dilution

Anti-TACC3 antibody [EPR7756] (Alexa Fluor® 488) - ab198539 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7756
ab198539 staining TACC3 in HeLa cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab198539 at 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at 1/250 dilution (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-TACC3 antibody [EPR7756] (Alexa Fluor® 647) - ab198542 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7756
ab198542 staining TACC3 in HeLa cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab198542 at 1/50 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at 1/250 dilution (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-TACC3 antibody [EPR7757] - ab134076 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7757
All lanes : Anti-TACC3 antibody [EPR7757] (ab134076) at 1/10000 dilutionLane 1 : HeLa cell lysateLane 2 : Jurkat cell lysateLane 3 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti-rabbit at 1/2000 dilution

Anti-ERIC-1 / TACC3 Antibody (aa689-838) - LS-C126344 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ERIC-1 / TACC3 Antibody (aa503-552) - LS-C116452 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TACC3 antibody LS-C116452 Western blot of NCI-H226 cell lysate.

Anti-ERIC-1 / TACC3 Antibody (Ser558) - LS-C191324 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ERIC-1 / TACC3 Antibody (Internal, clone EPR7757) - LS-C152469 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7757
Western blot analysis on (A) HeLa, (B) Jurkat, and (C) 293T cell lysates using anti-TACC3 antibody.

Anti-ERIC-1 / TACC3 Antibody (aa764-813) - LS-C200743 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HepG2 cells using TACC3 antibody.

Anti-ERIC-1 / TACC3 Antibody (aa789-838) - LS-C120496 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human tonsil tissue, using TACC3 Antibody. The picture on the right is treated with the synthesized peptide.
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