Gene Symbol | TACC3 |
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Entrez Gene | 10460 |
Alt Symbol | ERIC-1, ERIC1 |
Species | Human |
Gene Type | protein-coding |
Description | transforming, acidic coiled-coil containing protein 3 |
Other Description | transforming acidic coiled-coil-containing protein 3 |
Swissprots | Q3KQS5 Q2NKK4 Q9Y6A5 Q9UMQ1 |
Accessions | EAW82574 EAW82575 Q9Y6A5 AA682436 AF093543 AAD25964 AF479620 AAN76993 AI684124 AJ243997 CAB53009 AK225631 AK302463 BAG63753 AK304579 BAG65367 AK310660 BC106071 AAI06072 BC111771 AAI11772 DB098941 U38441 XM_005247929 XP_005247986 XM_005247930 XP_005247987 XM_011513386 XP_011511688 XM_011513387 XP_011511689 NM_006342 NP_006333 |
Function | Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May be involved in the control of cell growth and differentiation. May contribute to cancer. {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Top Pathways | RNA transport |
TACC3 CRISPR/Cas9 KO Plasmid (h) - sc-402461 from Santa Cruz Biotechnology
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TACC3 HDR Plasmid (h) - sc-402461-HDR from Santa Cruz Biotechnology
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TACC3 Double Nickase Plasmid (h) - sc-402461-NIC from Santa Cruz Biotechnology
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TACC3 Double Nickase Plasmid (h2) - sc-402461-NIC-2 from Santa Cruz Biotechnology
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TACC3 CRISPR Activation Plasmid (h) - sc-402461-ACT from Santa Cruz Biotechnology
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TACC3 CRISPR Activation Plasmid (h2) - sc-402461-ACT-2 from Santa Cruz Biotechnology
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TACC3 Lentiviral Activation Particles (h) - sc-402461-LAC from Santa Cruz Biotechnology
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TACC3 Lentiviral Activation Particles (h2) - sc-402461-LAC-2 from Santa Cruz Biotechnology
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TACC3 siRNA (h) - sc-36602 from Santa Cruz Biotechnology
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TACC3 shRNA Plasmid (h) - sc-36602-SH from Santa Cruz Biotechnology
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TACC3 shRNA (h) Lentiviral Particles - sc-36602-V from Santa Cruz Biotechnology
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TACC3 RNAi - H00010460-R01 from Novus Biologicals
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MISSION® esiRNA - EHU063201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20951 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00995 from Sigma-Aldrich
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TACC3 siRNA (Human) - CRH7098 from Cohesion Biosciences
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TACC3 - MBS8210520 from MyBioSource
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shRNA set against Human TACC3 (NM_006342.2) - SHH422440 from Creative biogene
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Human TACC3 siRNA - orb267600 from Biorbyt
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TACC3 shRNA Plasmid (Human) - CHH7098 from Cohesion Biosciences
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TACC3 miRNA 3'UTR clone - MiUTR3H-07555 from Creative biogene
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