Gene Symbol |
Zwint
|
Entrez Gene |
52696
|
Alt Symbol |
2010007E07Rik, 2600001N01Rik, D10Ertd749e, Zwint-1
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
ZW10 interactor
|
Other Description |
ZW10-interacting protein 1
|
Swissprots |
Q9CQU5 Q3UYT8 Q91VI4 Q9D0W9
|
Accessions |
EDL31942 EDL31943 EDL31944 Q9CQU5 AK004305 BAB23256 AK008144 BAB25492 AK013556 BAB28904 AK075977 BAC36090 AK082215 AK134380 BAE22123 AK170637 AK182584 AK184469 BC013559 AAH13559 BC027100 AAH27100 BC029087 BC034870 AAH34870 BY240779 NM_001293683 NP_001280612 NM_001293684 NP_001280613 NM_025635 NP_079911
|
Function |
Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Localizes to kinetochores from late prophase to anaphase. {ECO:0000250}.
|