Gene Symbol | Zwint |
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Entrez Gene | 52696 |
Alt Symbol | 2010007E07Rik, 2600001N01Rik, D10Ertd749e, Zwint-1 |
Species | Mouse |
Gene Type | protein-coding |
Description | ZW10 interactor |
Other Description | ZW10-interacting protein 1 |
Swissprots | Q9CQU5 Q3UYT8 Q91VI4 Q9D0W9 |
Accessions | EDL31942 EDL31943 EDL31944 Q9CQU5 AK004305 BAB23256 AK008144 BAB25492 AK013556 BAB28904 AK075977 BAC36090 AK082215 AK134380 BAE22123 AK170637 AK182584 AK184469 BC013559 AAH13559 BC027100 AAH27100 BC029087 BC034870 AAH34870 BY240779 NM_001293683 NP_001280612 NM_001293684 NP_001280613 NM_025635 NP_079911 |
Function | Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Localizes to kinetochores from late prophase to anaphase. {ECO:0000250}. |
ZWINT CRISPR/Cas9 KO Plasmid (m) - sc-424650 from Santa Cruz Biotechnology
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ZWINT HDR Plasmid (m) - sc-424650-HDR from Santa Cruz Biotechnology
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ZWINT Double Nickase Plasmid (m) - sc-424650-NIC from Santa Cruz Biotechnology
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ZWINT Double Nickase Plasmid (m2) - sc-424650-NIC-2 from Santa Cruz Biotechnology
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ZWINT CRISPR Activation Plasmid (m) - sc-424650-ACT from Santa Cruz Biotechnology
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ZWINT CRISPR Activation Plasmid (m2) - sc-424650-ACT-2 from Santa Cruz Biotechnology
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ZWINT Lentiviral Activation Particles (m) - sc-424650-LAC from Santa Cruz Biotechnology
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ZWINT Lentiviral Activation Particles (m2) - sc-424650-LAC-2 from Santa Cruz Biotechnology
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ZWINT siRNA (m) - sc-63264 from Santa Cruz Biotechnology
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ZWINT shRNA Plasmid (m) - sc-63264-SH from Santa Cruz Biotechnology
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ZWINT shRNA (m) Lentiviral Particles - sc-63264-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU027611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN45397 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND45397 from Sigma-Aldrich
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ZWINT siRNA (Mouse) - CRM5302 from Cohesion Biosciences
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ZWINT - MBS8213810 from MyBioSource
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shRNA set against Mouse ZWINT (NM_025635.3) - SHH456144 from Creative biogene
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shRNA set against Mouse Zwint(NM_025635.3) - SHL163740 from Creative biogene
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Mouse ZWINT siRNA - orb284778 from Biorbyt
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ZWINT shRNA Plasmid (Mouse) - CHM5302 from Cohesion Biosciences
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ZWINT miRNA 3'UTR clone - MiUTR1M-13226 from Creative biogene
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