Gene Symbol | CD1A |
---|---|
Entrez Gene | 909 |
Alt Symbol | CD1, FCB6, HTA1, R4, T6 |
Species | Human |
Gene Type | protein-coding |
Description | CD1a molecule |
Other Description | CD1A antigen, a polypeptide|T-cell surface antigen T6/Leu-6|T-cell surface glycoprotein CD1a|cluster of differentiation 1 A|cortical thymocyte antigen CD1A|differentiation antigen CD1-alpha-3|epidermal dendritic cell marker CD1a|hTa1 thymocyte antigen |
Swissprots | P06126 Q13962 D3DVD7 Q9UMM4 Q5TDJ8 Q9Y5M5 |
Accessions | AAA51932 AAA51934 AAD37578 EAW52843 EAW52844 P06126 AK312945 BAG35786 BC031645 AAH31645 CA432941 DB108750 DQ891346 ABM82272 DQ894526 ABM85452 M27735 AAA51933 M28825 AAA51931 X04450 CAA28049 X79308 X79309 XM_011510117 XP_011508419 XM_011510118 XP_011508420 NM_001763 NP_001754 |
Function | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. {ECO:0000269|PubMed:11231314, ECO:0000269|PubMed:16272286, ECO:0000269|PubMed:18178838}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Endosome membrane. Note=Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts. |
Tissue Specificity | Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. {ECO:0000269|PubMed:11231314, ECO:0000269|PubMed:18178838}. |
Top Pathways | Hematopoietic cell lineage |
CD1A CRISPR/Cas9 KO Plasmid (h) - sc-401734 from Santa Cruz Biotechnology
|
||||||||
CD1A HDR Plasmid (h) - sc-401734-HDR from Santa Cruz Biotechnology
|
||||||||
CD1A Double Nickase Plasmid (h) - sc-401734-NIC from Santa Cruz Biotechnology
|
||||||||
CD1A Double Nickase Plasmid (h2) - sc-401734-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CD1A CRISPR Activation Plasmid (h) - sc-401734-ACT from Santa Cruz Biotechnology
|
||||||||
CD1A CRISPR Activation Plasmid (h2) - sc-401734-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CD1A Lentiviral Activation Particles (h) - sc-401734-LAC from Santa Cruz Biotechnology
|
||||||||
CD1A Lentiviral Activation Particles (h2) - sc-401734-LAC-2 from Santa Cruz Biotechnology
|
||||||||
CD1A siRNA (h) - sc-42744 from Santa Cruz Biotechnology
|
||||||||
CD1A shRNA Plasmid (h) - sc-42744-SH from Santa Cruz Biotechnology
|
||||||||
CD1A shRNA (h) Lentiviral Particles - sc-42744-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU078881 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN5689 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5689 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR05081 from Sigma-Aldrich
|
||||||||
CD1A siRNA (Human) - CRH0638 from Cohesion Biosciences
|
||||||||
CD1A - MBS8217426 from MyBioSource
|
||||||||
shRNA set against Human CD1A (NM_001763.2) - SHH258581 from Creative biogene
|
||||||||
Human CD1A siRNA - orb261140 from Biorbyt
|
||||||||
CD1A shRNA Plasmid (Human) - CHH0638 from Cohesion Biosciences
|
||||||||
CD1A miRNA 3'UTR clone - MiUTR1H-01844 from Creative biogene
|