CD1A

Gene Symbol CD1A
Entrez Gene 909
Alt Symbol CD1, FCB6, HTA1, R4, T6
Species Human
Gene Type protein-coding
Description CD1a molecule
Other Description CD1A antigen, a polypeptide|T-cell surface antigen T6/Leu-6|T-cell surface glycoprotein CD1a|cluster of differentiation 1 A|cortical thymocyte antigen CD1A|differentiation antigen CD1-alpha-3|epidermal dendritic cell marker CD1a|hTa1 thymocyte antigen
Swissprots P06126 Q13962 D3DVD7 Q9UMM4 Q5TDJ8 Q9Y5M5
Accessions AAA51932 AAA51934 AAD37578 EAW52843 EAW52844 P06126 AK312945 BAG35786 BC031645 AAH31645 CA432941 DB108750 DQ891346 ABM82272 DQ894526 ABM85452 M27735 AAA51933 M28825 AAA51931 X04450 CAA28049 X79308 X79309 XM_011510117 XP_011508419 XM_011510118 XP_011508420 NM_001763 NP_001754
Function Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells. {ECO:0000269|PubMed:11231314, ECO:0000269|PubMed:16272286, ECO:0000269|PubMed:18178838}.
Subcellular Location Cell membrane; Single-pass type I membrane protein. Endosome membrane. Note=Subject to intracellular trafficking between the cell membrane and endosomes. Localizes to cell surface lipid rafts.
Tissue Specificity Expressed on cortical thymocytes, epidermal Langerhans cells, dendritic cells, on certain T-cell leukemias, and in various other tissues. {ECO:0000269|PubMed:11231314, ECO:0000269|PubMed:18178838}.
Top Pathways Hematopoietic cell lineage

CD1 (C-19) - sc-7091 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CD1 (C-19): sc-7091. Western blot analysis of CD1 expression in CCD-1064Sk whole cell lysate.

CD1A (CTB6) - sc-5265 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD1A (CTB6) PE: sc-5265 PE. FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

CD1A (HI149) - sc-19636 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD1A (HI149) PE: sc-19636 PE. FCM analysis of MOLT-4 cells. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

CD1A (O10) - sc-18885 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CD1A (O10): sc-18885. Immunofluorescence staining of methanol-fixed MOLT-4 cells showing membrane staining.

CD1A (NA1/34-HLK) - sc-80548 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

CD1A (NA1/34) - sc-53035 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

CD1A (N-19) - sc-7092 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CD1 antibody [SN13 K5-1B8] - ab95587 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone SN13 K5-1B8
Staining of Molt-4 cell line with 0.5 µg of Mouse IgG1 ? Isotype Control Purified (open histogram) or 0.5 µg of ab95587 (filled histogram) followed by Anti-Mouse IgG Biotin and Streptavidin PE. Total viable cells were used for analysis.

Anti-CD1a antibody - ab116649 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CD1a antibody (ab116649) at 1/100 dilution + MDA-MB231 cell line lysate at 35 µg

Anti-CD1a antibody - ab123133 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CD1a antibody (ab123133) at 1 µg/ml + 721_B cell lysate at 10 µgdeveloped using the ECL technique

Anti-CD1a antibody [7A7] - ab113618 from Abcam

Prices $387.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 7A7
All lanes : Anti-CD1a antibody [7A7] (ab113618) at 1/500 dilutionLane 1 : K562 cell lysateLane 2 : Raji cell lysateLane 3 : MOLT 4 cell lysate

Anti-CD1a antibody [C1A/711] - ab201337 from Abcam

Prices $359.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone C1A/711
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue labeling CD1a with ab201337 at 1 µg/ml.

Anti-CD1a antibody [CD1a007] - ab708 from Abcam

Prices $391.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone CD1a007
Ab708 positively staining acetone fixed, frozen human skin sections (1/25). The secondary Ab used was biotin conjugated anti mouse (1/1) and formed part of of a commercially available kit (Vector labs RTU ABC kit).This image is courtesy of an Abreview submitted on 11 October 2005. We do not have any further information relating to this image.

Anti-CD1a antibody [EP3091] - ab76531 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP3091
All lanes : Anti-CD1a antibody [EP3091] (ab76531) at 1/5000 dilutionLane 1 : MOLT4 lysateLane 2 : K562 lysateLane 3 : Fetal thymus lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CD1a antibody [EP3622] - ab108309 from Abcam

Prices $99.00
Sizes 10 µl
Host Rabbit
Clonality Monoclonal
Clone EP3622
All lanes : Anti-CD1a antibody [EP3622] (ab108309) at 1/1000 dilutionLane 1 : Human fetal thymus lysateLane 2 : T-78 cell lysate at 10 µgPerformed under reducing conditions.

Anti-CD1a antibody [HI149] - ab2574 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HI149

Anti-CD1a antibody [HI149] (Biotin) - ab134492 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HI149
Flow cytometric analysis of total viable MOLT4 cells labelling Human CD1a with ab134992 (filled histogram) at 0.125 µg or with 0.125 µg of Mouse IgG1 kappa Isotype Control Biotin (open histogram), followed by Streptavidin PE.

Anti-CD1a antibody [HI149] (CF405M) - ab117727 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HI149
ab117727 at 5 µl/106 cells staining CD1a in MOLT4 cells (yellow) and JURKAT cell line (blue). Total viable cells were used for analysis.

Anti-CD1a antibody [HI149] (FITC) - ab18231 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HI149

Anti-CD1a antibody [HI149] (PerCP) - ab91137 from Abcam

Prices $376.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HI149
Flow cytometry image generated using ab91137 and MOLT-4 cell line derived from a patient with acute lymphoblastic leukemia (ALL) in relapse.

Anti-CD1a antibody [HI149] (Phycoerythrin) - ab64597 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HI149

Anti-CD1a antibody [L21-A] - ab136922 from Abcam

Prices $376.00
Sizes 250 µl
Host Rabbit
Clonality Monoclonal
Clone L21-A
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue (4&microm) labelling CD1a with ab136922 at 1/100 dilution.

Anti-CD1a antibody [NA1/34] (Phycoerythrin) - ab22352 from Abcam

Prices $186.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone NA1/34

Anti-CD1a antibody [NA1/34-HLK] - ab24055 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone NA1/34-HLK

Anti-CD1a antibody [NA1/34-HLK] (Biotin) - ab27991 from Abcam

Prices $437.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone NA1/34-HLK
Ab27991, at a concentration of 10µl for 106 cells in 100µl, staining CD1a in MOLT4 cells by Flow Cytometry.
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