| Gene Symbol |
SLC7A9
|
| Entrez Gene |
11136
|
| Alt Symbol |
BAT1, CSNU3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
|
| Other Description |
B(0,+)-type amino acid transporter 1|b(0,+)AT|glycoprotein-associated amino acid transporter b0,+AT1|solute carrier family 7 (cationic amino acid transporter, y+ system), member 9|solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9
|
| Swissprots |
B2R9A6 P82251
|
| Accessions |
AAN40878 P82251 AB033548 BAB16840 AF141289 AAD55898 AJ249199 CAB54003 AK026446 AK223147 BAD96867 AK313708 BAG36453 AL365340 AL365341 AY170373 BC017962 AAH17962 BC029802 BP276659 CK300669 DQ892006 ABM82932 DQ895195 ABM86121 XM_006722992 XP_006723055 XM_011526402 XP_011524704 NM_001126335 NP_001119807 NM_001243036 NP_001229965 NM_014270 NP_055085
|
| Function |
Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high- affinity reabsorption of cystine in the kidney tubule. {ECO:0000269|PubMed:10471498, ECO:0000269|PubMed:10588648, ECO:0000269|PubMed:16609684}.
|
| Subcellular Location |
Apical cell membrane {ECO:0000269|PubMed:12167606, ECO:0000269|PubMed:16609684}; Multi- pass membrane protein {ECO:0000269|PubMed:16609684, ECO:0000305|PubMed:12167606}.
|
| Tissue Specificity |
Expressed in the brush border membrane in the kidney (at protein level). Kidney, small intestine, liver and placenta. {ECO:0000269|PubMed:10471498, ECO:0000269|PubMed:12167606}.
|
| Top Pathways |
Protein digestion and absorption
|