Gene Symbol | SLC7A9 |
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Entrez Gene | 11136 |
Alt Symbol | BAT1, CSNU3 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
Other Description | B(0,+)-type amino acid transporter 1|b(0,+)AT|glycoprotein-associated amino acid transporter b0,+AT1|solute carrier family 7 (cationic amino acid transporter, y+ system), member 9|solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9 |
Swissprots | B2R9A6 P82251 |
Accessions | AAN40878 P82251 AB033548 BAB16840 AF141289 AAD55898 AJ249199 CAB54003 AK026446 AK223147 BAD96867 AK313708 BAG36453 AL365340 AL365341 AY170373 BC017962 AAH17962 BC029802 BP276659 CK300669 DQ892006 ABM82932 DQ895195 ABM86121 XM_006722992 XP_006723055 XM_011526402 XP_011524704 NM_001126335 NP_001119807 NM_001243036 NP_001229965 NM_014270 NP_055085 |
Function | Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high- affinity reabsorption of cystine in the kidney tubule. {ECO:0000269|PubMed:10471498, ECO:0000269|PubMed:10588648, ECO:0000269|PubMed:16609684}. |
Subcellular Location | Apical cell membrane {ECO:0000269|PubMed:12167606, ECO:0000269|PubMed:16609684}; Multi- pass membrane protein {ECO:0000269|PubMed:16609684, ECO:0000305|PubMed:12167606}. |
Tissue Specificity | Expressed in the brush border membrane in the kidney (at protein level). Kidney, small intestine, liver and placenta. {ECO:0000269|PubMed:10471498, ECO:0000269|PubMed:12167606}. |
Top Pathways | Protein digestion and absorption |
SLC7A9 CRISPR/Cas9 KO Plasmid (h) - sc-416465 from Santa Cruz Biotechnology
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SLC7A9 HDR Plasmid (h) - sc-416465-HDR from Santa Cruz Biotechnology
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SLC7A9 Double Nickase Plasmid (h) - sc-416465-NIC from Santa Cruz Biotechnology
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SLC7A9 Double Nickase Plasmid (h2) - sc-416465-NIC-2 from Santa Cruz Biotechnology
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SLC7A9 CRISPR Activation Plasmid (h) - sc-416465-ACT from Santa Cruz Biotechnology
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SLC7A9 CRISPR Activation Plasmid (h2) - sc-416465-ACT-2 from Santa Cruz Biotechnology
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SLC7A9 Lentiviral Activation Particles (h) - sc-416465-LAC from Santa Cruz Biotechnology
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SLC7A9 Lentiviral Activation Particles (h2) - sc-416465-LAC-2 from Santa Cruz Biotechnology
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SLC7A9 siRNA (h) - sc-97173 from Santa Cruz Biotechnology
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SLC7A9 shRNA Plasmid (h) - sc-97173-SH from Santa Cruz Biotechnology
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SLC7A9 shRNA (h) Lentiviral Particles - sc-97173-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU129721 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19695 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19695 from Sigma-Aldrich
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SLC7A9 siRNA (Human) - CRH7619 from Cohesion Biosciences
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SLC7A9 RNAi - H00011136-R01 from Novus Biologicals
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SLC7A9 - MBS8218840 from MyBioSource
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shRNA set against Human SLC7A9 (NM_014270.4) - SHH412208 from Creative biogene
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Human SLC7A9 siRNA - orb268121 from Biorbyt
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SLC7A9 shRNA Plasmid (Human) - CHH7619 from Cohesion Biosciences
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SLC7A9 miRNA 3'UTR clone - MiUTR3H-06594 from Creative biogene
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SLC7A9 miRNA 3'UTR clone - MiUTR3H-06595 from Creative biogene
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