EXOSC9

Gene Symbol	EXOSC9
Entrez Gene	5393
Alt Symbol	PM/Scl-75, PMSCL1, RRP45, Rrp45p, p5, p6
Species	Human
Gene Type	protein-coding
Description	exosome component 9
Other Description	P75 polymyositis-scleroderma overlap syndrome associated autoantigen|P75 polymyositis-scleroderma overlap syndrome-associated autoantigen|PMSCL autoantigen, 75kD|autoantigen PM/Scl 1|exosome complex component RRP45|exosome complex exonuclease RRP45|polymyositis/scleroderma autoantigen 1, 75kDa
Swissprots	Q12883 Q86Y48 Q4W5P5 Q86Y41 Q06265
Accessions	AAY40968 EAX05247 EAX05248 EAX05249 EAX05250 EAX05251 EAX05252 Q06265 AJ505989 CAD44530 AJ517294 CAD56889 AK301967 BAG63380 AK307548 AK310894 BC012371 BC140038 AAI40039 BC140039 AAI40040 BC142978 AAI42979 BU615347 BX649106 M58460 AAA58384 U09215 AAA18832 XM_011532035 XP_011530337 NM_001034194 NP_001029366 NM_005033 NP_005024
Function	Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways
Subcellular Location	Isoform 2: Nucleus, nucleolus.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Exosome Component 9 protein fragment - ab159150 from Abcam Category Protein Source Wheat germ Species Human

EXOSC9 / p5 Antibody Blocking Peptide - LS-E22694 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EXOSC9 / p5 Antibody Blocking Peptide - LS-E26904 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Exosome Component 9 Partial Recombinant Protein - H00005393-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

EXOSC9-Antibody-N-term-Blocking-Peptide - BP9398a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

EXOSC9 blocking peptide - GTX88547-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

EXOSC9 Protein (OPPA00073) - OPPA00073 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source Sf9 insect cells.

Human EXOSC9 protein - orb168319 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

Goat anti EXOSC9 antibody Immunizing peptide - orb55038 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

Exosome Component 9 Peptide - AC21-1736-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

EXOSC9 - H00005393-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

EXOSC9 - H00005393-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Exosome Component 9, Human Recombinant - 228-12882-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

Recombinant Human Exosome Component 9 - 228-12882-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Sf9 insect cells. Species Human

Recombinant Human Exosome Component 9 - 228-12882-3 from RayBiotech Category Protein Source Sf9 insect cells. Species Human

Exosome Component 9 Peptide - 46-967P from ProSci Category Peptide Species Human

EXOSC9 fusion protein - Ag19768 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

EXOSC9 fusion protein - Ag19783 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Exosome Component 9 Protein - BP001969-PRO-126 from Syd Labs Category Protein Prices $160.00, $4,100.00 Sizes 10 µg, 1 mg Source Sf9 insect cells-derived. Species Human

EXOSC9 Human Protein - GWB-BSP580 from Genway Biotech Category Protein Prices $75.00, $165.00, $4,540.00 Sizes 2 μg, 10 μg, 1000 μg Source Sf9 insect cells. Species Human

EXOSC9 - NKX-532 from Reagent Proteins Category Protein Prices $364.00, $4,256.00 Sizes 10.00 µg, 1 mg Source Sf9 insect cells.

EXOSC9 (transcript variant 1) - TP323537 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PMSCL1, Peptide - MBS426291 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Exosome Component 9 Human Recombinant - Pr20623 from ProMab Category Protein Prices $50.00, $130.00, $4,100.00 Sizes 2 μg, 10 μg, 1 mg Source Sf9 insect cells. Species Human

Exosome Component 9 Protein - NBP1-87369PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

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