EXOSC9

Gene Symbol EXOSC9
Entrez Gene 5393
Alt Symbol PM/Scl-75, PMSCL1, RRP45, Rrp45p, p5, p6
Species Human
Gene Type protein-coding
Description exosome component 9
Other Description P75 polymyositis-scleroderma overlap syndrome associated autoantigen|P75 polymyositis-scleroderma overlap syndrome-associated autoantigen|PMSCL autoantigen, 75kD|autoantigen PM/Scl 1|exosome complex component RRP45|exosome complex exonuclease RRP45|polymyositis/scleroderma autoantigen 1, 75kDa
Swissprots Q12883 Q86Y48 Q4W5P5 Q86Y41 Q06265
Accessions AAY40968 EAX05247 EAX05248 EAX05249 EAX05250 EAX05251 EAX05252 Q06265 AJ505989 CAD44530 AJ517294 CAD56889 AK301967 BAG63380 AK307548 AK310894 BC012371 BC140038 AAI40039 BC140039 AAI40040 BC142978 AAI42979 BU615347 BX649106 M58460 AAA58384 U09215 AAA18832 XM_011532035 XP_011530337 NM_001034194 NP_001029366 NM_005033 NP_005024
Function Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways
Subcellular Location Isoform 2: Nucleus, nucleolus.
Top Pathways RNA degradation

EXOSC9 (D-6) - sc-271815 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EXOSC9 (D-6): sc-271815. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear and cytoplasmic localization.

EXOSC9 (H-300) - sc-135118 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
EXOSC9 (H-300): sc-135118. Western blot analysis of EXOSC9 expression in non-transfected: sc-117752 (A) and mouse EXOSC9 transfected: sc-120144 (B) 293T whole cell lysates.

EXOSC9 (K-13) - sc-162781 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EXOSC9 (S-16) - sc-162782 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EXOSC9 (2337C3a) - sc-81087 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
EXOSC9 (2337C3a): sc-81087 Western Blot analysis of human recombinant EXOSC9 fusion protein.

Anti-Exosome Component 9 antibody - ab156686 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Exosome Component 9 antibody (ab156686) at 0.1 µg/mlLane 1 : 293T whole cell lysate at 50 µgLane 2 : 293T whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 50 µgLane 4 : Jurkat whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-Exosome Component 9 antibody - ab85703 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Exosome Component 9 antibody (ab85703) at 0.3 µg/ml + Jurkat cell lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-Exosome Component 9 antibody [2337C3a] - ab54283 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2337C3a
Staining of recombinant immunising protein using anti-Exosome component 9 antibody [2337C3a] (ab54283).

Anti-EXOSC9 / p5 Antibody - LS-C65799 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-EXOSC9 / p5 Antibody (Biotin) - LS-C180655 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EXOSC9 / p5 Antibody (DY650) - LS-C180656 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EXOSC9 / p5 Antibody (DY488) - LS-C180657 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EXOSC9 / p5 Antibody (N-Terminus) - LS-C145727 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EXOSC9 antibody LS-C145727 Western blot of Fetal Heart lysate. Antibody concentration 1 ug/ml.

Anti-EXOSC9 / p5 Antibody (HRP) - LS-C180658 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EXOSC9 / p5 Antibody (aa429-441) - LS-C112772 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
EXOSC9 antibody (0.3 ug/ml) staining of Jurkat lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-EXOSC9 / p5 Antibody (DY550) - LS-C180659 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EXOSC9 / p5 Antibody (clone 2337C3a) - LS-C184554 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 2337C3a

Anti-EXOSC9 / p5 Antibody (clone 2337C3a) - LS-C342590 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2337C3a
Western blot analysis of immunized recombinant protein, using anti-EXOSC9 monoclonal antibody.

Anti-EXOSC9 / p5 Antibody - LS-C180109 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: Exosome Component 9 Antibody - Staining of EXOSC9 in mouse prostate.

Anti-EXOSC9 / p5 Antibody (aa389-439) - LS-C290535 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human EXOSC9 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-EXOSC9 antibody used for IP at 6 ug/mg lysate. EXOSC9 was also immunoprecipitated by rabbit anti-EXOSC9 antibody BL14017. For blotting immunoprecipitated EXOSC9, was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.

Exosome Component 9 Antibody - NBP1-71702 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Exosome Component 9 Antibody [NBP1-71702] - Analysis of EXOSC9 in A. HepG2 cell lysate and B. MCF7 cell lysate.

Exosome Component 9 Antibody - NBP2-22242 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Exosome Component 9 Antibody [NBP2-22242] - Whole cell lysate (15 and 50 ug) from mouse NIH3T3 cells. NBP2-22242 used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.

Exosome Component 9 Antibody - NBP1-28490 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Exosome Component 9 Antibody [Alexa Fluor (R) 700] - NBP1-71702AF700 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal

Exosome Component 9 Antibody [Alexa Fluor (R) 647] - NBP1-71702AF647 from Novus Biologicals

Prices $319.00
Sizes 100 tests
Host Rabbit
Clonality Polyclonal
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