| Gene Symbol |
LCOR
|
| Entrez Gene |
84458
|
| Alt Symbol |
MLR2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ligand dependent nuclear receptor corepressor
|
| Other Description |
ligand-dependent corepressor|mblk1-related protein 2
|
| Swissprots |
D3DR47 Q8N3L6 Q86T33 Q96JN0 Q5VW16 Q86T32 Q7Z723
|
| Accessions |
EAW49962 EAW49963 EAW49964 EAW49965 EAW49966 Q96JN0 AB058698 BAB47424 AB072899 AK023248 AK095345 AL832044 CAD91160 AL832106 CAD91159 AL834245 CAD38921 BC053359 AAH53359 BC128542 AAI28543 DA507116 DA788606 HQ448101 ADQ32582 XM_006718033 XP_006718096 XM_006718034 XP_006718097 XM_011540277 XP_011538579 NM_001170765 NP_001164236 NM_001170766 NP_001164237 NM_032440 NP_115816
|
| Function |
May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3' (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand- dependent transcription activation by ESR1, ESR2, NR3C1, PGR, RARA, RARB, RARG, RXRA and VDR. {ECO:0000250, ECO:0000269|PubMed:12535528}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00320, ECO:0000269|PubMed:12535528}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:12535528}.
|
![Western Blot: LCOR Overexpression Lysate (Adult Normal) [NBP2-06026] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LCOR.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1958_LCOR%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06026-img0001.jpg)