COL3A1

Gene Symbol COL3A1
Entrez Gene 1281
Alt Symbol EDS4A
Species Human
Gene Type protein-coding
Description collagen, type III, alpha 1
Other Description Ehlers-Danlos syndrome type IV, autosomal dominant|alpha1 (III) collagen|collagen alpha-1(III) chain|collagen, fetal
Swissprots Q541P8 Q7KZ56 Q9UC91 Q6LDJ2 Q15112 P02461 Q9UC90 Q6LDB3 Q16403 Q6LDJ3 D2JYH5 D3DPH4 P78429 Q9UC89 V9GZI1 R4N3C5 Q8N6U4 Q9UC88 Q53S91
Accessions AAA51999 AAA52000 AAA52001 AAA52002 AAA52040 AAA52041 AAD13937 AAL13167 AAY24164 ACZ58371 AGL34959 CDM55397 CDM55578 EAX10909 EAX10910 EAX10911 P02461 AI755052 AK091853 AK308010 BC028178 AAH28178 BP374999 M11134 AAA52004 M13146 AAA52003 M59227 AAB59383 S79877 AAB35615 X01655 CAA25821 X01742 CAA25878 X06700 CAA29886 X07240 CAA30229 X14420 CAA32583 X15332 CAA33387 NM_000090 NP_000081
Function Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}.
Top Pathways Focal adhesion, ECM-receptor interaction, Amoebiasis, Protein digestion and absorption, PI3K-Akt signaling pathway

COL3A1 (B-10) - sc-271249 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
COL3A1 (B-10): sc-271249. Western blot analysis of COL3A1 expression in non-transfected 293T: sc-117752 (A), human COL3A1 transfected 293T: sc-114750 (B) and HISM (C) whole cell lysates.

COL3A1 (C-15) - sc-8781 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
COL3A1 (C-15): sc-8781. Immunofluorescence staining of methanol-fixed Hs68 cells showing cytoplasmic localization.

COL3A1 (H-300) - sc-28888 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
COL3A1 (H-300): sc-28888. Western blot analysis of COL3A1 expression in non-transfected: sc-117752 (A) and human COL3A1 transfected: sc-114750 (B) 293T whole cell lysates.

Pro-COL3A1 (A-1) - sc-166333 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pro-COL3A1 (A-1): sc-166333. Western blot analysis of COL3A1 expression in non-transfected: sc-117752 (A) and human COL3A1 transfected: sc-114750 (B) 293T whole cell lysates.

Pro-COL3A1 (B-4) - sc-166316 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Pro-COL3A1 (B-4): sc-166316. Western blot analysis of COL3A1 expression in non-transfected: sc-117752 (A) and human COL3A1 transfected: sc-114750 (B) 293T whole cell lysates.

Pro-COL3A1 (N-18) - sc-8779 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pro-COL3A1 (N-18): sc-8779. Western blot analysis of COL3A1 expression in non-transfected: sc-117752 (A) and human COL3A1 transfected: sc-114750 (B) 293T whole cell lysates.

Anti-Collagen III antibody - ab59436 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Collagen III in human pancreas tissue (paraffin section) using ab59436 (1/500 dilution); in the presence or absence of immuninzing peptide.

Anti-Collagen III antibody - ab24119 from Abcam

Prices $378.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal
ab24119 staining Collagen III in pig epithelial tissue by Immunohistochemistry (Frozen sections).Tissue was fixed in acetone and then incubated with ab24119 at a 1/10 dilution for 1 hour at 25°C. The secondary used was ab98650 Goat F(ab')2 polyclonal Secondary Antibody to Mouse IgM - mu chain, used at a 1/1000 dilution. DAPI (Blue) stained for nuclei. Far Red stains for Collagen III.See Abreview

Anti-Collagen III antibody - ab83829 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Collagen III antibody (ab83829) at 1 µg/mlLane 1 : Skin (Human) Tissue Lysate - adult normal tissue (ab30166)Lane 2 : Small Intestine (Human) Tissue Lysate - adult normal tissue (ab29276)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal Secondary Antibody to Rabbit IgG - H&L (HRP), pre-adsorbed at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Collagen III antibody - ab24129 from Abcam

Host Goat
Clonality Polyclonal

Anti-Collagen III antibody [1E7-D7/Col3] - ab23445 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E7-D7/Col3
Immunohistochemical analysis of frozen pig skin tissue, staining Collagen III with ab23445.Tissue was fixed with acetone and blocked with 10% serum for 10 minutes 20&degC. Samples were incubated with primary antibody (1/500 in TBS, 0.02% Triton x-100, 2% BSA) for 16 hours at 4&degC. An undiluted biotin-conjugated goat anti-mouse polyclonal IgG was used as the secondary antibody. See Abreview

Anti-Collagen III antibody (Biotin) - ab24823 from Abcam

Prices $372.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Collagen III antibody [Col-29] - ab82354 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Col-29
IHC image of Collagen III staining in Human normal skin formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab82354, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Collagen III antibody [FH-7A] - ab6310 from Abcam

Prices $401.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone FH-7A
Staining of formalin-fixed, paraffin-embedded rat skin with 1:4,000 ab6310 using biotin/ExtrAvidin®-Peroxidase.

Anti-COL3A1 / Collagen III Antibody (Biotin) - LS-C211310 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-COL3A1 / Collagen III Antibody (HRP) - LS-C211307 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-COL3A1 / Collagen III Antibody - LS-C211308 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-COL3A1 / Collagen III Antibody (FITC) - LS-C211309 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-COL3A1 / Collagen III Antibody (aa1409-1438, APC) - LS-C255237 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL3A1 / Collagen III Antibody (aa1409-1438, AP) - LS-C255236 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL3A1 / Collagen III Antibody (aa1409-1438, Biotin) - LS-C255238 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL3A1 / Collagen III Antibody (aa1409-1438, FITC) - LS-C255239 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL3A1 / Collagen III Antibody (aa1172-1221) - LS-C121066 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from A549 cells, treated with etoposide 25 uM 24h, using Collagen III alpha1 (Cleaved-Gly1221) Antibody. The lane on the right is treated with the synthesized peptide.

Anti-COL3A1 / Collagen III Antibody (aa1409-1438, PE) - LS-C255240 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-COL3A1 / Collagen III Antibody (aa1409-1438, Azide-free, HRP) - LS-C255241 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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