Gene Symbol | SH2D3C |
---|---|
Entrez Gene | 10044 |
Alt Symbol | CHAT, NSP3, PRO34088, SHEP1 |
Species | Human |
Gene Type | protein-coding |
Description | SH2 domain containing 3C |
Other Description | SH2 domain-containing Eph receptor-binding protein 1|SH2 domain-containing protein 3C|novel SH2-containing protein 3 |
Swissprots | Q8N6X3 Q8N5H7 E9PG48 Q5JU31 Q5HYE5 A8K5S8 Q9Y2X5 Q6UY42 |
Accessions | EAW87695 Q8N5H7 AF124251 AAD28246 AI472242 AI799905 AJ420431 AK056068 BAG51614 AK096983 BAG53404 AK128287 AK291393 BAF84082 AK292041 BAF84730 AK292718 BAF85407 AK294386 BAG57643 AK311510 AY358089 AAQ88456 AY358440 AAQ89948 BC027962 AAH27962 BC032365 AAH32365 BI912337 BX647905 CAI46101 CU454732 CU455802 DA054525 DA970566 DB161948 DC302682 JF432256 ADZ15473 XM_005251639 XP_005251696 XM_011518114 XP_011516416 XM_011518115 XP_011516417 XM_011518116 XP_011516418 XM_011518117 XP_011516419 NM_001142531 NP_001136003 NM_001142532 NP_001136004 NM_001142533 NP_001136005 NM_001142534 NP_001136006 NM_001252334 NP_001239263 NM_005489 NP_005480 NM_170600 NP_733745 |
Function | Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associated with the membrane when EGF-stimulated. Found at ruffling membranes (By similarity). {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:10187783}. |
NSP3 CRISPR/Cas9 KO Plasmid (h) - sc-407380 from Santa Cruz Biotechnology
|
||||||||
NSP3 HDR Plasmid (h) - sc-407380-HDR from Santa Cruz Biotechnology
|
||||||||
NSP3 Double Nickase Plasmid (h) - sc-407380-NIC from Santa Cruz Biotechnology
|
||||||||
NSP3 Double Nickase Plasmid (h2) - sc-407380-NIC-2 from Santa Cruz Biotechnology
|
||||||||
NSP3 CRISPR Activation Plasmid (h) - sc-407380-ACT from Santa Cruz Biotechnology
|
||||||||
NSP3 CRISPR Activation Plasmid (h2) - sc-407380-ACT-2 from Santa Cruz Biotechnology
|
||||||||
NSP3 Lentiviral Activation Particles (h) - sc-407380-LAC from Santa Cruz Biotechnology
|
||||||||
NSP3 Lentiviral Activation Particles (h2) - sc-407380-LAC-2 from Santa Cruz Biotechnology
|
||||||||
NSP3 siRNA (h) - sc-44855 from Santa Cruz Biotechnology
|
||||||||
NSP3 shRNA Plasmid (h) - sc-44855-SH from Santa Cruz Biotechnology
|
||||||||
NSP3 shRNA (h) Lentiviral Particles - sc-44855-V from Santa Cruz Biotechnology
|
||||||||
SH2D3C RNAi - H00010044-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU159141 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19251 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19251 from Sigma-Aldrich
|
||||||||
SH2D3C siRNA (Human) - CRH6760 from Cohesion Biosciences
|
||||||||
SH2D3C RNAi - H00010044-R02 from Novus Biologicals
|
||||||||
SH2D3C - MBS8232029 from MyBioSource
|
||||||||
shRNA set against Human SH2D3C (NM_005489.3) - SHH406540 from Creative biogene
|
||||||||
NSP3 CRISPR/Cas9 KO Plasmid (h2) - sc-407380-KO-2 from Santa Cruz Biotechnology
|
||||||||
NSP3 HDR Plasmid (h2) - sc-407380-HDR-2 from Santa Cruz Biotechnology
|
||||||||
Human SH2D3C siRNA - orb267262 from Biorbyt
|
||||||||
SH2D3C shRNA Plasmid (Human) - CHH6760 from Cohesion Biosciences
|
||||||||
SH2D3C miRNA 3'UTR clone - MiUTR3H-07036 from Creative biogene
|
||||||||
SH2D3C miRNA 3'UTR clone - MiUTR3H-07037 from Creative biogene
|