Gene Symbol | SH2D3C |
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Entrez Gene | 10044 |
Alt Symbol | CHAT, NSP3, PRO34088, SHEP1 |
Species | Human |
Gene Type | protein-coding |
Description | SH2 domain containing 3C |
Other Description | SH2 domain-containing Eph receptor-binding protein 1|SH2 domain-containing protein 3C|novel SH2-containing protein 3 |
Swissprots | Q8N6X3 Q8N5H7 E9PG48 Q5JU31 Q5HYE5 A8K5S8 Q9Y2X5 Q6UY42 |
Accessions | EAW87695 Q8N5H7 AF124251 AAD28246 AI472242 AI799905 AJ420431 AK056068 BAG51614 AK096983 BAG53404 AK128287 AK291393 BAF84082 AK292041 BAF84730 AK292718 BAF85407 AK294386 BAG57643 AK311510 AY358089 AAQ88456 AY358440 AAQ89948 BC027962 AAH27962 BC032365 AAH32365 BI912337 BX647905 CAI46101 CU454732 CU455802 DA054525 DA970566 DB161948 DC302682 JF432256 ADZ15473 XM_005251639 XP_005251696 XM_011518114 XP_011516416 XM_011518115 XP_011516417 XM_011518116 XP_011516418 XM_011518117 XP_011516419 NM_001142531 NP_001136003 NM_001142532 NP_001136004 NM_001142533 NP_001136005 NM_001142534 NP_001136006 NM_001252334 NP_001239263 NM_005489 NP_005480 NM_170600 NP_733745 |
Function | Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Associated with the membrane when EGF-stimulated. Found at ruffling membranes (By similarity). {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:10187783}. |
NSP3 (M-15) - sc-11696 from Santa Cruz Biotechnology
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NSP3 (H-92) - sc-292732 from Santa Cruz Biotechnology
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NSP3 (J-16.1) - sc-100792 from Santa Cruz Biotechnology
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p-NSP3 (Tyr 793) - sc-33050 from Santa Cruz Biotechnology
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Anti-NSP3 antibody - ab126130 from Abcam
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Anti-NSP3 antibody - ab56950 from Abcam
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Anti-NSP3 antibody - ab172563 from Abcam
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Anti-NSP3 antibody - ab89803 from Abcam
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Anti-NSP3 antibody [EPR13493] - ab181246 from Abcam
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Anti-SH2D3C / NSP3 Antibody (aa780-792) - LS-C132095 from LifeSpan Bioscience
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Anti-SH2D3C / NSP3 Antibody (aa179-228) - LS-C111498 from LifeSpan Bioscience
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Anti-SH2D3C / NSP3 Antibody (aa1-111, Azide-free) - LS-C330654 from LifeSpan Bioscience
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Anti-SH2D3C / NSP3 Antibody - LS-C195012 from LifeSpan Bioscience
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Anti-SH2D3C / NSP3 Antibody (clone 3B2) - LS-C133619 from LifeSpan Bioscience
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Anti-SH2D3C / NSP3 Antibody (C-Terminus) - LS-C155252 from LifeSpan Bioscience
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SH2D3C Antibody - NBP2-20341 from Novus Biologicals
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SH2D3C Antibody (3B2) - H00010044-M01 from Novus Biologicals
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SH2D3C Antibody - NBP1-58841 from Novus Biologicals
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SH2D3C Antibody - NBP2-13306 from Novus Biologicals
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SH2D3C Antibody (2E3) - H00010044-M02 from Novus Biologicals
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SH2D3C Antibody (1B6) - H00010044-M04 from Novus Biologicals
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SH2D3C Antibody (2G1) - H00010044-M05 from Novus Biologicals
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SH2D3C Antibody - H00010044-D01P from Novus Biologicals
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SH2D3C Antibody (3C5) - H00010044-M07 from Novus Biologicals
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SH2D3C Antibody - H00010044-B01P from Novus Biologicals
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