TGFB1

Gene Symbol	TGFB1
Entrez Gene	100033900
Alt Symbol	-
Species	Horse
Gene Type	protein-coding
Description	transforming growth factor, beta 1
Other Description	TGF-beta-1|transforming growth factor beta 1|transforming growth factor beta-1
Swissprots	Q9TUM8 O19011
Accessions	O19011 AF175709 AAD49431 HM569606 ADK90115 X99438 CAA67801 XM_005596086 XP_005596143 NM_001081849 NP_001075318
Function	Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T- helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells. {ECO:0000250|UniProtKB:P04202}.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Top Pathways	Hippo signaling pathway, Tuberculosis, MAPK signaling pathway, Pancreatic cancer, Renal cell carcinoma

• Antibodies
• Assays/Kits
• Proteins/Peptides

Horse TGFb1 ELISA Kit - abx150474 from Abbexa Category ELISA Kit Sensitivity 5.9 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Transforming Growth Factor Beta 1 (TGFb1), Horse, ELISA Kit - SEA124Eq from ARP American Research Products Category ELISA Kit Prices $794.00 Sizes 96 t Sensitivity 6.3pg/mL Range 15.6-1,000pg/mL

Transforming growth factor beta-1 (TGFB1), Horse, ELISA Kit - CSB-EL023446HO from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

transforming growth factor, beta 1, ELISA Kit - MBS934513 from MyBioSource Category ELISA Kit Prices $550.00, $795.00, $2,890.00, $5,465.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of horse TGFB1 is typically less than 1.56 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest horse TGFB1 concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 3.12 pg/ml -200 pg/ml.

Horse Transforming growth factor beta-1(TGFB1) ELISA kit - CSB-EL023446HO from Cusabio Category ELISA Kit Sensitivity 1.56pg/ml. Range 3.12 pg/ml-200 pg/ml

Horse Transforming Growth Factor Beta 1 (TGFb1) ELISA Kit - EKU07799 from Biomatik Category ELISA Kit Prices $813.00, $3,576.00, $6,502.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 28 pg/mL Range 78-5000 pg/mL

Transforming Growth Factor Beta 1 (TGFb1), Equine, ELISA Kit - DL-TGFb1-Eq from ARP American Research Products Category ELISA Kit Prices $745.00 Sizes 96 t Range 15.6-1,000 pg/mL

Horse TGFb1 ELISA Kit - abx574744 from Abbexa Category ELISA Kit Sensitivity 6.3 pg/ml Range 15.625 pg/ml - 1000 pg/ml

Horse Transforming growth factor beta-1 (TGFB1) ELISA Kit - EKC32373 from Biomatik Category ELISA Kit Prices $795.00, $3,021.00, $5,645.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 1.56 pg/ml Range 3.12 pg/ml-200 pg/ml

Horse TGFB1 ELISA Kit - E100183 from Biobool Category ELISA Kit

TGFB1 ELISA Kit (Horse) (OKCD01225) - OKCD01225 from Aviva Systems Biology Category ELISA Kit Prices $590.00 Sizes 96 wells Sensitivity < 28 pg/mL Range 78-5,000 pg/mL

Transforming Growth Factor Beta 1 (TGFb1), ELISA Kit - MBS451079 from MyBioSource Category ELISA Kit Prices $405.00, $535.00, $2,350.00, $4,565.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <6.3pg/mL Range 15.6-1000pg/mL

Search more