EPB41L3

Gene Symbol EPB41L3
Entrez Gene 23136
Alt Symbol 4.1B, DAL-1, DAL1
Species Human
Gene Type protein-coding
Description erythrocyte membrane protein band 4.1-like 3
Other Description band 4.1-like protein 3|differentially expressed in adenocarcinoma of the lung protein 1
Swissprots O95713 B7Z4I5 Q9Y2J2 F5GX05 Q9BRP5
Accessions CAY55963 EAX01644 EAX01645 Q9Y2J2 AB023204 BAA76831 AF069072 AAC79806 AF515797 AAM48247 AK090875 AK094952 BAG52962 AK128531 BAG54690 AK292583 BAF85272 AK294610 BAH11823 AK294690 BAH11849 AK295453 BAH12074 AK297406 BAH12571 AK303679 BAH14014 AK307751 AK307904 AK314438 BAG37049 AL832598 BC006141 AAH06141 BC008377 AAH08377 DA317127 DB301724 XM_011525606 XP_011523908 XM_011525607 XP_011523909 XM_011525608 XP_011523910 XM_011525609 XP_011523911 XM_011525610 XP_011523912 XM_011525611 XP_011523913 XM_011525612 XP_011523914 XM_011525613 XP_011523915 XM_011525614 XP_011523916 XM_011525615 XP_011523917 XM_011525616 XP_011523918 XM_011525617 XP_011523919 XM_011525618 XP_011523920 XM_011525619 XP_011523921 XM_011525620 XP_011523922 XM_011525621 XP_011523923 XM_011525622 XP_011523924 XM_011525623 XP_011523925 XM_011525624 XP_011523926 XM_011525625 XP_011523927 XM_011525626 XP_011523928 XM_011525627 XP_011523929 XM_011525628 XP_011523930 XM_011525629 XP_011523931 XM_011525630 XP_011523932 XM_011525631 XP_011523933 XM_011525632 XP_011523934 XM_011525633 XP_011523935 XM_011525634 XP_011523936 XM_011525635 XP_011523937 XM_011525636 XP_011523938 XM_011525637 XP_011523939 NM_001281533 NP_001268462 NM_001281534 NP_001268463 NM_001281535 NP_001268464 NM_012307 NP_036439
Function Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, including PRMT3 and PRMT5. {ECO:0000269|PubMed:15334060, ECO:0000269|PubMed:15737618, ECO:0000269|PubMed:16420693, ECO:0000269|PubMed:9892180}.
Subcellular Location Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction {ECO:0000269|PubMed:9892180}. Cell membrane {ECO:0000269|PubMed:9892180}; Peripheral membrane protein {ECO:0000269|PubMed:9892180}; Cytoplasmic side {ECO:0000269|PubMed:9892180}. Cytoplasm {ECO:0000269|PubMed:9892180}. Note=Detected in the cytoplasm of actively dividing cells.
Tissue Specificity Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung. {ECO:0000269|PubMed:9892180}.
Top Pathways Tight junction

4.1B (A-7) - sc-514386 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
4.1B (A-7): sc-514386. Western blot analysis of 4.1B expression in Neuro-2A (A) and HL-60 (B) whole cell lysates.

4.1B (B-6) - sc-398089 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
4.1B (B-6): sc-398089. Western blot analysis of 4.1B expression in Neuro-2A (A) and HEL 92.1.7 (B) whole cell lysates.

4.1B (K-18) - sc-25965 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
4.1B (K-18): sc-25965. Immunofluorescence staining of methanol-fixed KNRK cells showing cytoplasmic localization.

4.1B (E-20) - sc-25964 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

4.1B (485) - sc-100641 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
4.1B (485): sc-100641. Western blot analysis of 4.1B expression in Hep G2 whole cell lysate.

Anti-EPB41L3 antibody - ab40831 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-EPB41L3 antibody (ab40831) at 1 µg/ml + Human brain lysate at 35 µg

Anti-EPB41L3 antibody - ab57039 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-EPB41L3 antibody - ab65368 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-EPB41L3 antibody (ab65368) at 2 µg/ml + HeLa whole cell lysate

Anti-EPB41L3 antibody - C-terminal - ab154071 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EPB41L3 antibody - C-terminal (ab154071) at 1/1000 dilutionLane 1 : PC3 whole cell lysateLane 2 : U-87 MG whole cell lysateLysates/proteins at 30 µg per lane.

Anti-EPB41L3 Antibody (aa1075-1087) - LS-C54792 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (1 ug/ml) staining of human brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-EPB41L3 Antibody - LS-C307932 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-EPB41L3 Antibody - LS-C310265 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EPB41L3 Antibody (aa915-1008) - LS-C307934 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-EPB41L3 Antibody (aa400-500) - LS-C83790 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Band 4.1 in mouse brain lysate.

Anti-EPB41L3 Antibody (N-Terminus) - LS-C345661 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of E41L3 Antibody with human Fetal Lung lysate.

Anti-EPB41L3 Antibody (Internal, Biotin) - LS-C141720 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EPB41L3 Antibody (Internal, DY650) - LS-C141721 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EPB41L3 Antibody (Internal, DY488) - LS-C141722 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EPB41L3 Antibody (Internal, HRP) - LS-C141723 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EPB41L3 Antibody (Internal, DY550) - LS-C141724 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EPB41L3 Antibody (aa915-1008, clone 10C96, Azide-free) - LS-C183596 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10C96

EPB41L3 Antibody - NB110-61027 from Novus Biologicals

Prices $99.00, $279.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal

EPB41L3 Antibody - NBP1-89372 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: EPB41L3 Antibody [NBP1-89372] - Lane 1: Marker  [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.  Lane 2: Human cell line RT-4.  Lane 3: Human cell line U-251MG sp

EPB41L3 Antibody (2B1) - H00023136-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2B1

EPB41L3 Antibody - NB100-2435 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: EPB41L3 Antibody [NB100-2435] - (1ug/ml) staining of human brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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