Gene Symbol | EPB41L3 |
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Entrez Gene | 23136 |
Alt Symbol | 4.1B, DAL-1, DAL1 |
Species | Human |
Gene Type | protein-coding |
Description | erythrocyte membrane protein band 4.1-like 3 |
Other Description | band 4.1-like protein 3|differentially expressed in adenocarcinoma of the lung protein 1 |
Swissprots | O95713 B7Z4I5 Q9Y2J2 F5GX05 Q9BRP5 |
Accessions | CAY55963 EAX01644 EAX01645 Q9Y2J2 AB023204 BAA76831 AF069072 AAC79806 AF515797 AAM48247 AK090875 AK094952 BAG52962 AK128531 BAG54690 AK292583 BAF85272 AK294610 BAH11823 AK294690 BAH11849 AK295453 BAH12074 AK297406 BAH12571 AK303679 BAH14014 AK307751 AK307904 AK314438 BAG37049 AL832598 BC006141 AAH06141 BC008377 AAH08377 DA317127 DB301724 XM_011525606 XP_011523908 XM_011525607 XP_011523909 XM_011525608 XP_011523910 XM_011525609 XP_011523911 XM_011525610 XP_011523912 XM_011525611 XP_011523913 XM_011525612 XP_011523914 XM_011525613 XP_011523915 XM_011525614 XP_011523916 XM_011525615 XP_011523917 XM_011525616 XP_011523918 XM_011525617 XP_011523919 XM_011525618 XP_011523920 XM_011525619 XP_011523921 XM_011525620 XP_011523922 XM_011525621 XP_011523923 XM_011525622 XP_011523924 XM_011525623 XP_011523925 XM_011525624 XP_011523926 XM_011525625 XP_011523927 XM_011525626 XP_011523928 XM_011525627 XP_011523929 XM_011525628 XP_011523930 XM_011525629 XP_011523931 XM_011525630 XP_011523932 XM_011525631 XP_011523933 XM_011525632 XP_011523934 XM_011525633 XP_011523935 XM_011525634 XP_011523936 XM_011525635 XP_011523937 XM_011525636 XP_011523938 XM_011525637 XP_011523939 NM_001281533 NP_001268462 NM_001281534 NP_001268463 NM_001281535 NP_001268464 NM_012307 NP_036439 |
Function | Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, including PRMT3 and PRMT5. {ECO:0000269|PubMed:15334060, ECO:0000269|PubMed:15737618, ECO:0000269|PubMed:16420693, ECO:0000269|PubMed:9892180}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction {ECO:0000269|PubMed:9892180}. Cell membrane {ECO:0000269|PubMed:9892180}; Peripheral membrane protein {ECO:0000269|PubMed:9892180}; Cytoplasmic side {ECO:0000269|PubMed:9892180}. Cytoplasm {ECO:0000269|PubMed:9892180}. Note=Detected in the cytoplasm of actively dividing cells. |
Tissue Specificity | Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung. {ECO:0000269|PubMed:9892180}. |
Top Pathways | Tight junction |
4.1B (A-7) - sc-514386 from Santa Cruz Biotechnology
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4.1B (B-6) - sc-398089 from Santa Cruz Biotechnology
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4.1B (K-18) - sc-25965 from Santa Cruz Biotechnology
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4.1B (E-20) - sc-25964 from Santa Cruz Biotechnology
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4.1B (485) - sc-100641 from Santa Cruz Biotechnology
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Anti-EPB41L3 antibody - ab40831 from Abcam
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Anti-EPB41L3 antibody - ab57039 from Abcam
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Anti-EPB41L3 antibody - ab65368 from Abcam
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Anti-EPB41L3 antibody - C-terminal - ab154071 from Abcam
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Anti-EPB41L3 Antibody (aa1075-1087) - LS-C54792 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody - LS-C307932 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody - LS-C310265 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody (aa915-1008) - LS-C307934 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody (aa400-500) - LS-C83790 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody (N-Terminus) - LS-C345661 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody (Internal, Biotin) - LS-C141720 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody (Internal, DY650) - LS-C141721 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody (Internal, DY488) - LS-C141722 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody (Internal, HRP) - LS-C141723 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody (Internal, DY550) - LS-C141724 from LifeSpan Bioscience
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Anti-EPB41L3 Antibody (aa915-1008, clone 10C96, Azide-free) - LS-C183596 from LifeSpan Bioscience
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EPB41L3 Antibody - NB110-61027 from Novus Biologicals
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EPB41L3 Antibody - NBP1-89372 from Novus Biologicals
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EPB41L3 Antibody (2B1) - H00023136-M01 from Novus Biologicals
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EPB41L3 Antibody - NB100-2435 from Novus Biologicals
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