EPB41L3
| Gene Symbol | EPB41L3 |
|---|---|
| Entrez Gene | 23136 |
| Alt Symbol | 4.1B, DAL-1, DAL1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | erythrocyte membrane protein band 4.1-like 3 |
| Other Description | band 4.1-like protein 3|differentially expressed in adenocarcinoma of the lung protein 1 |
| Swissprots | O95713 B7Z4I5 Q9Y2J2 F5GX05 Q9BRP5 |
| Accessions | CAY55963 EAX01644 EAX01645 Q9Y2J2 AB023204 BAA76831 AF069072 AAC79806 AF515797 AAM48247 AK090875 AK094952 BAG52962 AK128531 BAG54690 AK292583 BAF85272 AK294610 BAH11823 AK294690 BAH11849 AK295453 BAH12074 AK297406 BAH12571 AK303679 BAH14014 AK307751 AK307904 AK314438 BAG37049 AL832598 BC006141 AAH06141 BC008377 AAH08377 DA317127 DB301724 XM_011525606 XP_011523908 XM_011525607 XP_011523909 XM_011525608 XP_011523910 XM_011525609 XP_011523911 XM_011525610 XP_011523912 XM_011525611 XP_011523913 XM_011525612 XP_011523914 XM_011525613 XP_011523915 XM_011525614 XP_011523916 XM_011525615 XP_011523917 XM_011525616 XP_011523918 XM_011525617 XP_011523919 XM_011525618 XP_011523920 XM_011525619 XP_011523921 XM_011525620 XP_011523922 XM_011525621 XP_011523923 XM_011525622 XP_011523924 XM_011525623 XP_011523925 XM_011525624 XP_011523926 XM_011525625 XP_011523927 XM_011525626 XP_011523928 XM_011525627 XP_011523929 XM_011525628 XP_011523930 XM_011525629 XP_011523931 XM_011525630 XP_011523932 XM_011525631 XP_011523933 XM_011525632 XP_011523934 XM_011525633 XP_011523935 XM_011525634 XP_011523936 XM_011525635 XP_011523937 XM_011525636 XP_011523938 XM_011525637 XP_011523939 NM_001281533 NP_001268462 NM_001281534 NP_001268463 NM_001281535 NP_001268464 NM_012307 NP_036439 |
| Function | Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, including PRMT3 and PRMT5. {ECO:0000269|PubMed:15334060, ECO:0000269|PubMed:15737618, ECO:0000269|PubMed:16420693, ECO:0000269|PubMed:9892180}. |
| Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction {ECO:0000269|PubMed:9892180}. Cell membrane {ECO:0000269|PubMed:9892180}; Peripheral membrane protein {ECO:0000269|PubMed:9892180}; Cytoplasmic side {ECO:0000269|PubMed:9892180}. Cytoplasm {ECO:0000269|PubMed:9892180}. Note=Detected in the cytoplasm of actively dividing cells. |
| Tissue Specificity | Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung. {ECO:0000269|PubMed:9892180}. |
| Top Pathways | Tight junction |
EPB41L3 peptide (1075-1087) - ab45836 from Abcam
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Human EPB41L3 full length protein - ab132471 from Abcam
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EPB41L3 Antibody Blocking Peptide - LS-E25994 from LifeSpan Bioscience
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Recombinant Human EPB41L3 Protein - H00023136-Q01 from Novus Biologicals
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Recombinant Human EPB41L3 Protein - H00023136-P01 from Novus Biologicals
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EPB41L3-Antibody-N-term-Blocking-Peptide - BP14602a from Abgent, a WuXi AppTec company
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EPB41L3 blocking peptide - GTX89463-PEP from GeneTex
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EPB41L3 Peptide - AC21-0822-P from Abcore
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EPB41L3 - H00023136-P01-10 from Acris Antibodies
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EPB41L3 - H00023136-P01-25 from Acris Antibodies
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EPB41L3 - H00023136-Q01-10 from Acris Antibodies
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EPB41L3 - H00023136-Q01-25 from Acris Antibodies
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EPB41L3 Peptide - 45-543P from ProSci
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EPB41L3 fusion protein - Ag1089 from Proteintech Group
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Recombinant Human EPB41L3, His-tagged - EPB41L3-28576TH from Creative Biomart
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Recombinant Human EPB41L3, GST-tagged - EPB41L3-12479H from Creative Biomart
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EPB41L3/DAL1, Peptide - MBS427001 from MyBioSource
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EPB41L3 Protein - NBP1-89372PEP from Novus Biologicals
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EPB41L3 Peptide, Human - M34GP04972H from Creative Peptides
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EPB41L3 Immunizing peptide - orb17244 from Biorbyt
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