| Gene Symbol | HADH |
|---|---|
| Entrez Gene | 3033 |
| Alt Symbol | HAD, HADH1, HADHSC, HCDH, HHF4, MSCHAD, SCHAD |
| Species | Human |
| Gene Type | protein-coding |
| Description | hydroxyacyl-CoA dehydrogenase |
| Other Description | L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain|hydroxyacyl-coenzyme A dehydrogenase, mitochondrial|medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase|short-chain 3-hydroxyacyl-CoA dehydrogenase |
| Swissprots | O00324 J3KQ17 Q16836 Q4W5B4 O00753 O00397 |
| Accessions | AAB58153 AAD13581 AAY41050 EAX06218 EAX06219 EAX06220 Q16836 AF001902 AAB54008 AF001903 AAB54009 AI017358 AK096018 BAG53198 AK314444 BAG37053 BC000306 AAH00306 BM682975 DA825380 DQ891419 ABM82345 DQ894593 ABM85519 X96752 CAA65528 XM_005262972 XP_005263029 XR_938726 NM_001184705 NP_001171634 NM_005327 NP_005318 |
| Function | Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA. |
| Subcellular Location | Mitochondrion matrix. |
| Tissue Specificity | Expressed in liver, kidney, pancreas, heart and skeletal muscle. |
| Top Pathways | Lysine degradation, Fatty acid elongation, Fatty acid degradation, Tryptophan metabolism, Valine, leucine and isoleucine degradation |