Gene Symbol | HADH |
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Entrez Gene | 3033 |
Alt Symbol | HAD, HADH1, HADHSC, HCDH, HHF4, MSCHAD, SCHAD |
Species | Human |
Gene Type | protein-coding |
Description | hydroxyacyl-CoA dehydrogenase |
Other Description | L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain|hydroxyacyl-coenzyme A dehydrogenase, mitochondrial|medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase|short-chain 3-hydroxyacyl-CoA dehydrogenase |
Swissprots | O00324 J3KQ17 Q16836 Q4W5B4 O00753 O00397 |
Accessions | AAB58153 AAD13581 AAY41050 EAX06218 EAX06219 EAX06220 Q16836 AF001902 AAB54008 AF001903 AAB54009 AI017358 AK096018 BAG53198 AK314444 BAG37053 BC000306 AAH00306 BM682975 DA825380 DQ891419 ABM82345 DQ894593 ABM85519 X96752 CAA65528 XM_005262972 XP_005263029 XR_938726 NM_001184705 NP_001171634 NM_005327 NP_005318 |
Function | Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA. |
Subcellular Location | Mitochondrion matrix. |
Tissue Specificity | Expressed in liver, kidney, pancreas, heart and skeletal muscle. |
Top Pathways | Lysine degradation, Fatty acid elongation, Fatty acid degradation, Tryptophan metabolism, Valine, leucine and isoleucine degradation |
HADHSC CRISPR/Cas9 KO Plasmid (h) - sc-406791 from Santa Cruz Biotechnology
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HADHSC HDR Plasmid (h) - sc-406791-HDR from Santa Cruz Biotechnology
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HADHSC Double Nickase Plasmid (h) - sc-406791-NIC from Santa Cruz Biotechnology
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HADHSC Double Nickase Plasmid (h2) - sc-406791-NIC-2 from Santa Cruz Biotechnology
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HADHSC CRISPR Activation Plasmid (h) - sc-406791-ACT from Santa Cruz Biotechnology
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HADHSC CRISPR Activation Plasmid (h2) - sc-406791-ACT-2 from Santa Cruz Biotechnology
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HADHSC Lentiviral Activation Particles (h) - sc-406791-LAC from Santa Cruz Biotechnology
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HADHSC Lentiviral Activation Particles (h2) - sc-406791-LAC-2 from Santa Cruz Biotechnology
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HADHSC siRNA (h) - sc-75222 from Santa Cruz Biotechnology
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HADHSC shRNA Plasmid (h) - sc-75222-SH from Santa Cruz Biotechnology
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HADHSC shRNA (h) Lentiviral Particles - sc-75222-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU093571 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9856 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9856 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06565 from Sigma-Aldrich
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HADH siRNA (Human) - CRH2061 from Cohesion Biosciences
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HADH RNAi - H00003033-R01 from Novus Biologicals
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HADH - MBS8238768 from MyBioSource
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Human HADH siRNA - orb262563 from Biorbyt
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HADH shRNA Plasmid (Human) - CHH2061 from Cohesion Biosciences
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