| Gene Symbol |
HADH
|
| Entrez Gene |
3033
|
| Alt Symbol |
HAD, HADH1, HADHSC, HCDH, HHF4, MSCHAD, SCHAD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
hydroxyacyl-CoA dehydrogenase
|
| Other Description |
L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain|hydroxyacyl-coenzyme A dehydrogenase, mitochondrial|medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase|short-chain 3-hydroxyacyl-CoA dehydrogenase
|
| Swissprots |
O00324 J3KQ17 Q16836 Q4W5B4 O00753 O00397
|
| Accessions |
AAB58153 AAD13581 AAY41050 EAX06218 EAX06219 EAX06220 Q16836 AF001902 AAB54008 AF001903 AAB54009 AI017358 AK096018 BAG53198 AK314444 BAG37053 BC000306 AAH00306 BM682975 DA825380 DQ891419 ABM82345 DQ894593 ABM85519 X96752 CAA65528 XM_005262972 XP_005263029 XR_938726 NM_001184705 NP_001171634 NM_005327 NP_005318
|
| Function |
Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA.
|
| Subcellular Location |
Mitochondrion matrix.
|
| Tissue Specificity |
Expressed in liver, kidney, pancreas, heart and skeletal muscle.
|
| Top Pathways |
Lysine degradation, Fatty acid elongation, Fatty acid degradation, Tryptophan metabolism, Valine, leucine and isoleucine degradation
|