Gene Symbol | FRMPD2 |
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Entrez Gene | 143162 |
Alt Symbol | PDZD5C, PDZK4, PDZK5C |
Species | Human |
Gene Type | protein-coding |
Description | FERM and PDZ domain containing 2 |
Other Description | FERM and PDZ domain-containing protein 2|PDZ domain containing 5C|PDZ domain-containing protein 4 |
Swissprots | Q6ZN38 Q68DX3 Q2VY07 B7WNW0 Q8N5T9 Q6ZWI2 Q6GMQ9 B7ZML5 |
Accessions | EAW93139 EAW93140 EAW93141 Q68DX3 AK123038 BAC85520 AK131386 BAD18537 AK303923 BAG64851 AY491519 AAS79660 BC031614 AAH31614 BC040910 BC073954 AAH73954 BC144636 AAI44637 BC144639 AAI44640 BC156408 AAI56409 BC157131 AAI57132 CR749241 CAH18097 DC342800 DC425871 HG502882 HQ447524 ADQ32010 XM_011539322 XP_011537624 XM_011539323 XP_011537625 XM_011539324 XP_011537626 XM_011539325 XP_011537627 XM_011539326 XP_011537628 XM_011539327 XP_011537629 XR_945606 NM_001017929 NM_152428 NM_001018071 NP_001018081 NM_001042512 NP_001035977 |
Function | May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). {ECO:0000269|PubMed:19706687}. |
Subcellular Location | Cytoplasm {ECO:0000305}. Basolateral cell membrane {ECO:0000269|PubMed:19706687}. Cell junction, tight junction {ECO:0000269|PubMed:19706687}. Note=Colocalizes with CTNNB1, CDH1 and PKP4 at the basolateral membrane. Colocalizes with TJP1 at tight junctions. Its recruitment to cell-cell contacts requires CDH1. |
Tissue Specificity | Expressed in epithelial cells. {ECO:0000269|PubMed:19706687}. |
Human FRMPD2 full length protein - ab165496 from Abcam
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FRMPD2 Antibody Blocking Peptide - LS-E30800 from LifeSpan Bioscience
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FRMPD2 Antibody Blocking Peptide - LS-E24438 from LifeSpan Bioscience
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Recombinant Human FRMPD2 Protein - H00143162-P01 from Novus Biologicals
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FRMPD2 Blocking Peptide - NBP1-77083PEP from Novus Biologicals
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FRMPD2 Peptide - GTX85236-PEP from GeneTex
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FRMPD2 - H00143162-P01-10 from Acris Antibodies
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FRMPD2 - H00143162-P01-25 from Acris Antibodies
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FRMPD2 control peptide - AP26197CP-N from Acris Antibodies
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FRMPD2 Peptide - 5455P from ProSci
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Recombinant Human FERM and PDZ domain-containing protein 2(FRMPD2) ,partial - CSB-YP737874HU CSB-EP737874HU CSB-BP737874HU CSB-MP737874HU from Cusabio
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FRMPD2 Protein - NBP2-33436PEP from Novus Biologicals
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FRMPD2 Peptide, Human - M34GP05911H from Creative Peptides
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FERM and PDZ domain-containing protein 2 (FRMPD2), partial, Recombinant Protein - MBS1370637 from MyBioSource
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