Gene Symbol | FRMPD2 |
---|---|
Entrez Gene | 143162 |
Alt Symbol | PDZD5C, PDZK4, PDZK5C |
Species | Human |
Gene Type | protein-coding |
Description | FERM and PDZ domain containing 2 |
Other Description | FERM and PDZ domain-containing protein 2|PDZ domain containing 5C|PDZ domain-containing protein 4 |
Swissprots | Q6ZN38 Q68DX3 Q2VY07 B7WNW0 Q8N5T9 Q6ZWI2 Q6GMQ9 B7ZML5 |
Accessions | EAW93139 EAW93140 EAW93141 Q68DX3 AK123038 BAC85520 AK131386 BAD18537 AK303923 BAG64851 AY491519 AAS79660 BC031614 AAH31614 BC040910 BC073954 AAH73954 BC144636 AAI44637 BC144639 AAI44640 BC156408 AAI56409 BC157131 AAI57132 CR749241 CAH18097 DC342800 DC425871 HG502882 HQ447524 ADQ32010 XM_011539322 XP_011537624 XM_011539323 XP_011537625 XM_011539324 XP_011537626 XM_011539325 XP_011537627 XM_011539326 XP_011537628 XM_011539327 XP_011537629 XR_945606 NM_001017929 NM_152428 NM_001018071 NP_001018081 NM_001042512 NP_001035977 |
Function | May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2). {ECO:0000269|PubMed:19706687}. |
Subcellular Location | Cytoplasm {ECO:0000305}. Basolateral cell membrane {ECO:0000269|PubMed:19706687}. Cell junction, tight junction {ECO:0000269|PubMed:19706687}. Note=Colocalizes with CTNNB1, CDH1 and PKP4 at the basolateral membrane. Colocalizes with TJP1 at tight junctions. Its recruitment to cell-cell contacts requires CDH1. |
Tissue Specificity | Expressed in epithelial cells. {ECO:0000269|PubMed:19706687}. |
FRMPD2 CRISPR/Cas9 KO Plasmid (h) - sc-410320 from Santa Cruz Biotechnology
|
||||||||
FRMPD2 HDR Plasmid (h) - sc-410320-HDR from Santa Cruz Biotechnology
|
||||||||
FRMPD2 Double Nickase Plasmid (h) - sc-410320-NIC from Santa Cruz Biotechnology
|
||||||||
FRMPD2 Double Nickase Plasmid (h2) - sc-410320-NIC-2 from Santa Cruz Biotechnology
|
||||||||
FRMPD2 CRISPR Activation Plasmid (h) - sc-410320-ACT from Santa Cruz Biotechnology
|
||||||||
FRMPD2 CRISPR Activation Plasmid (h2) - sc-410320-ACT-2 from Santa Cruz Biotechnology
|
||||||||
FRMPD2 Lentiviral Activation Particles (h) - sc-410320-LAC from Santa Cruz Biotechnology
|
||||||||
FRMPD2 Lentiviral Activation Particles (h2) - sc-410320-LAC-2 from Santa Cruz Biotechnology
|
||||||||
FRMPD2 siRNA (h) - sc-90419 from Santa Cruz Biotechnology
|
||||||||
FRMPD2 shRNA Plasmid (h) - sc-90419-SH from Santa Cruz Biotechnology
|
||||||||
FRMPD2 shRNA (h) Lentiviral Particles - sc-90419-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU013631 from Sigma-Aldrich
|
||||||||
MISSION® esiRNA - EHU116841 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN8951 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8951 from Sigma-Aldrich
|
||||||||
FRMPD2 siRNA (Human) - CRJ5363 from Cohesion Biosciences
|
||||||||
FRMPD2 - MBS8213437 from MyBioSource
|
||||||||
shRNA set against Human FRMPD2 (NM_001018071.3) - SHH297201 from Creative biogene
|
||||||||
FRMPD2 shRNA Plasmid (Human) - CHJ5363 from Cohesion Biosciences
|
||||||||
FRMPD2 miRNA 3'UTR clone - MiUTR3H-12842 from Creative biogene
|