Gene Symbol | ORMDL3 |
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Entrez Gene | 94103 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ORMDL sphingolipid biosynthesis regulator 3 |
Other Description | ORM1-like protein 3 |
Swissprots | Q6UY83 Q8N138 B3KS83 |
Accessions | CAC24860 CAF85976 CAF86524 CAK32168 EAW60616 EAW60617 EAW60618 EAW60619 EAW60620 Q8N138 AF151043 AAF36129 AF373101 AAN76521 AF373102 AAN76522 AF395708 AAM43507 AK074811 BAC11223 AK075212 BAC11476 AK093063 BAG52645 AX775843 CAE11621 AY357943 AAQ57273 BC000638 BC017087 AAH17087 BC018837 BC050710 BC054042 BC071833 AAH71833 DB127807 HQ447484 ADQ31970 XM_005257825 XP_005257882 XM_005257827 XP_005257884 NM_139280 NP_644809 |
Function | Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling. {ECO:0000269|PubMed:20182505}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:12093374, ECO:0000269|PubMed:19819884}; Multi- pass membrane protein {ECO:0000269|PubMed:12093374, ECO:0000269|PubMed:19819884}. |
Tissue Specificity | Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus. {ECO:0000269|PubMed:12093374}. |
Human ORMDL3 full length protein - ab164963 from Abcam
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ORMDL3 Antibody Blocking Peptide - LS-E455 from LifeSpan Bioscience
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ORMDL3 Antibody Blocking Peptide - LS-E23471 from LifeSpan Bioscience
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Recombinant Human ORMDL3 Protein - H00094103-P01 from Novus Biologicals
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ORMDL3-Antibody-Center-Blocking-peptide - BP10739c from Abgent, a WuXi AppTec company
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ORM1-like protein 3 - H00094103-P01 from Acris Antibodies
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ORM1-like protein 3 - H00094103-P01-10 from Acris Antibodies
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ORM1-like protein 3 - H00094103-P01-25 from Acris Antibodies
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ORMDL3 fusion protein - ag10182 from Proteintech Group
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ORMDL3 fusion protein - ag10391 from Proteintech Group
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Recombinant Human ORMDL3 - ORMDL3-967H from Creative Biomart
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ORM1-like protein 3 - TP302279 from Acris Antibodies
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ORMDL3 Peptide, Human - M34GP11133H from Creative Peptides
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ORM1-like protein 3 (ORMDL3), Recombinant Protein - MBS7025209 from MyBioSource
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Recombinant Human ORMDL3 Protein, GST-tagged - ORMDL3-185H from Creative Biomart
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