EPHA1

Gene Symbol	EPHA1
Entrez Gene	2041
Alt Symbol	EPH, EPHT, EPHT1
Species	Human
Gene Type	protein-coding
Description	EPH receptor A1
Other Description	eph tyrosine kinase 1|ephrin type-A receptor 1|erythropoietin-producing hepatoma amplified sequence|erythropoietin-producing hepatoma receptor|hEpha1|oncogene EPH|soluble EPHA1 variant 1|soluble EPHA1 variant 2|tyrosine-protein kinase receptor EPH
Swissprots	Q15405 B5A966 B5A967 A1L3V3 P21709
Accessions	AAD43440 AAS07458 CCQ43308 EAL23789 EAW51845 EAW51846 EAW51847 P21709 AA723562 AA723620 AA788809 AI057542 AK290351 BAF83040 AK313263 AU131228 BC130291 AAI30292 BC144156 CD653381 CN289899 CN289901 EU826604 ACF47640 EU826605 ACF47641 M18391 AAA36747 Z27409 CAA81796 XM_006715880 XP_006715943 XM_011515878 XP_011514180 XR_428169 NM_005232 NP_005223
Function	Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis. {ECO:0000269|PubMed:17634955, ECO:0000269|PubMed:19118217, ECO:0000269|PubMed:20043122}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:19118217}; Single-pass type I membrane protein {ECO:0000269|PubMed:19118217}.
Tissue Specificity	Overexpressed in several carcinomas.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EPHA1 / EPH Receptor A1 ELISA Kit (Sandwich ELISA) - LS-F4578 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.124 ng/ml Range 0.313-20 ng/ml

Human EPHA1 / EPH Receptor A1 ELISA Kit (Cell-Based ELISA) - LS-F1963 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.313-20 ng/ml

Phosphotyrosine EPHA1 / Ephrin Type-A Receptor 1 ELISA Kit - RAB0942 from Sigma-Aldrich Category ELISA Kit Prices $637.00 Sizes 1 kt

Human Phospho-EphA1 DuoSet IC ELISA, 2 Plate - DYC4835-2 from R&D Systems Category ELISA Kit Prices $329.00 Sizes 1 kit (for 2 Plates)

Human Total EphA1 DuoSet IC ELISA - DYC638-2 from R&D Systems Category ELISA Kit Prices $329.00 Sizes 1 kit (for 2 Plates) Range 156.00 - 10,000 pg/mL

Human EPHA1 ELISA Kit - abx151424 from Abbexa Category ELISA Kit Sensitivity 0.124 ng/ml Range 0.313 ng/ml - 20 ng/ml

Ephrin Type A Receptor 1, EPHA1, Human, ELISA Kit - E-EL-H1044 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.188 Range 0.313-20ng/mL

Ephrin Type A Receptor 1 (EPHA1), Human, ELISA Kit - SEB368Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 0.124ng/mL Range 0.312-20ng/mL

Ephrin type-A receptor 1 (EPHA1), Human, ELISA Kit - CSB-EL007720HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Ephrin Type A Receptor 1, EPHA1, Rabbit, ELISA Kit - E-EL-RB1725 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Ephrin Type A Receptor 1, EPHA1, Chicken, ELISA Kit - E-EL-Ch0237 from ARP American Research Products Category ELISA Kit Prices $445.50 Sizes 96 t

Ephrin Type A Receptor 1, EPHA1, Porcine, ELISA Kit - E-EL-P0989 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Ephrin Type A Receptor 1, EPHA1, Sheep, ELISA Kit - E-EL-S0894 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Ephrin Type A Receptor 1, EPHA1, Guinea Pig, ELISA Kit - E-EL-GP0205 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Ephrin Type A Receptor 1, EPHA1, Monkey, ELISA Kit - E-EL-MK1204 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Custom Human EphA1 ELISA - ELH-EPHA1 from RayBiotech Category ELISA Kit Prices $615.00, $1,107.00, $2,460.00 Sizes 1 plate kit, 2 plate kit, 5 plate kit

EPH receptor A1, ELISA Kit - MBS923323 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human EPHA1 is typically less than 0.039 ng/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.156 ng/m -10 ng/ml.

EPHA1, ELISA Kit - MBS2501143 from MyBioSource Category ELISA Kit Prices $490.00, $585.00, $2,475.00, $4,360.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

EPHA1, ELISA Kit - MBS2505285 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

EPHA1, ELISA Kit - MBS2503243 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

EPHA1, ELISA Kit - MBS2510937 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313-20ng/mL

EPHA1, ELISA Kit - MBS2510294 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 75pg/mL Range 125-8000pg/mL

EPHA1, ELISA Kit - MBS2510072 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.188ng/mL Range 0.313--20ng/mL

EPHA1, ELISA Kit - MBS2505978 from MyBioSource Category ELISA Kit Prices $450.00, $535.00, $2,255.00, $3,975.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

EPHA1 Colorimetric Cell-Based ELISA Kit - CB5231 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

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