NFKBIB

Gene Symbol	NFKBIB
Entrez Gene	4793
Alt Symbol	IKBB, TRIP9
Species	Human
Gene Type	protein-coding
Description	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
Other Description	I-kappa-B-beta|NF-kappa-B inhibitor beta|NF-kappa-BIB|TR-interacting protein 9|TRIP-9|ikB-B|ikB-beta|ikappaBbeta|thyroid receptor-interacting protein 9
Swissprots	Q15653 A8K3F4 Q96BJ7
Accessions	AAC41742 AAU10088 EAW56839 EAW56840 EAW56841 EAW56842 EAW56843 Q15653 AA044256 AB209784 BAD93021 AB362577 BAF81542 AI684894 AK057862 BAB71599 AK290569 BAF83258 BC007197 AAH07197 BC015528 AAH15528 BI520169 BM008311 BM449613 BQ440907 BT006743 AAP35389 BU150265 BU634404 BX111397 DA633677 DQ890633 ABM92250 DQ893804 ABM84730 XM_006723226 XP_006723289 XM_006723227 XP_006723290 NM_001243116 NP_001230045 NM_002503 NP_002494 NR_040515 NM_001001716
Function	Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Tissue Specificity	Expressed in all tissues examined.
Top Pathways	Cytosolic DNA-sensing pathway, Influenza A, Herpes simplex infection, Measles, Epstein-Barr virus infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human IKB beta full length protein - ab123184 from Abcam Category Protein Source E. coli Species Human

Human IKB beta full length protein - ab85246 from Abcam Category Protein Source E. coli Species Human

IKB beta peptide - ab7548 from Abcam Category Peptide

NFKBIB / IKB Beta / IKBB Antibody Blocking Peptide - LS-E2701 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFKBIB / IKB Beta / IKBB Antibody Blocking Peptide - LS-E12179 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFKBIB / IKB Beta / IKBB Antibody Blocking Peptide - LS-E12180 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFKBIB / IKB Beta / IKBB Antibody Blocking Peptide - LS-E12239 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NFKBIB / IKB Beta / IKBB Antibody Blocking Peptide - LS-E12240 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IkB-beta Recombinant Protein - H00004793-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

IkB-beta Partial Recombinant Protein - H00004793-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

IkB-beta Recombinant Protein - H00004793-P02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

IkB-beta Peptide - NBP1-96921 from Novus Biologicals Category Peptide Prices $169.00 Sizes 50 µg

Recombinant Human IkB-beta Protein - NBP1-99091 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

NFKBIB-Antibody-C-term-Blocking-peptide - BP13780b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human NFKBIB protein - orb168923 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 5 μg, 20 μg Source E. coli Species Human

NFKBIB peptide - orb217669 from Biorbyt Category Peptide Prices $306.00, $519.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

NFKBIB protein (His tag) - 80R-2172 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

NFKBIB / IKBB (1-356, His-tag) - AR50253PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

NFKBIB / IKBB (1-356, His-tag) - AR50253PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

NFKBIB / IKBB - H00004793-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NFKBIB / IKBB - H00004793-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NFKBIB / IKBB - H00004793-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

NFKBIB / IKBB - H00004793-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

NFKBIB / IKBB - H00004793-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

NFKBIB / IKBB - H00004793-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

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