NFKBIB

Gene Symbol NFKBIB
Entrez Gene 4793
Alt Symbol IKBB, TRIP9
Species Human
Gene Type protein-coding
Description nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
Other Description I-kappa-B-beta|NF-kappa-B inhibitor beta|NF-kappa-BIB|TR-interacting protein 9|TRIP-9|ikB-B|ikB-beta|ikappaBbeta|thyroid receptor-interacting protein 9
Swissprots Q15653 A8K3F4 Q96BJ7
Accessions AAC41742 AAU10088 EAW56839 EAW56840 EAW56841 EAW56842 EAW56843 Q15653 AA044256 AB209784 BAD93021 AB362577 BAF81542 AI684894 AK057862 BAB71599 AK290569 BAF83258 BC007197 AAH07197 BC015528 AAH15528 BI520169 BM008311 BM449613 BQ440907 BT006743 AAP35389 BU150265 BU634404 BX111397 DA633677 DQ890633 ABM92250 DQ893804 ABM84730 XM_006723226 XP_006723289 XM_006723227 XP_006723290 NM_001243116 NP_001230045 NM_002503 NP_002494 NR_040515 NM_001001716
Function Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Tissue Specificity Expressed in all tissues examined.
Top Pathways Cytosolic DNA-sensing pathway, Influenza A, Herpes simplex infection, Measles, Epstein-Barr virus infection

IκB-β siRNA (h) - sc-29362 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IκB-β shRNA Plasmid (h) - sc-29362-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IκB-β shRNA (h) Lentiviral Particles - sc-29362-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

IkB-beta RNAi - H00004793-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

IkB-beta RNAi - H00004793-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU149541 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15255 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15255 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08571 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08571

NFKBIB siRNA (Human) - CRH3180 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NFKBIB (NM_002503.4) - SHH351908 from Creative biogene

Category siRNA
Species Reactivities Human

Human NFKBIB siRNA - orb263682 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NFKBIB shRNA Plasmid (Human) - CHH3180 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NFKBIB miRNA 3'UTR clone - MiUTR3H-06852 from Creative biogene

Species Reactivities Human
Search more