Gene Symbol |
NPM2
|
Entrez Gene |
10361
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
nucleophosmin/nucleoplasmin 2
|
Other Description |
nucleoplasmin-2
|
Swissprots |
Q86SE8 Q6NVH6 D3DSQ8 B3KSU0
|
Accessions |
EAW63730 EAW63731 EAW63732 Q86SE8 AK094267 BAG52852 AK127602 AY262113 AAP33134 AY262114 AAP33135 BC068078 AAH68078 DB262972 XM_011544359 XP_011542661 XM_011544360 XP_011542662 XM_011544361 XP_011542663 XM_011544362 XP_011542664 XM_011544363 XP_011542665 XM_011544364 XP_011542666 NM_001286680 NP_001273609 NM_001286681 NP_001273610 NM_182795 NP_877724
|
Function |
Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization. {ECO:0000269|PubMed:21863821}.
|
Subcellular Location |
Nucleus {ECO:0000250}. Note=Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm. {ECO:0000250}.
|