Gene Symbol | NPM2 |
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Entrez Gene | 10361 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | nucleophosmin/nucleoplasmin 2 |
Other Description | nucleoplasmin-2 |
Swissprots | Q86SE8 Q6NVH6 D3DSQ8 B3KSU0 |
Accessions | EAW63730 EAW63731 EAW63732 Q86SE8 AK094267 BAG52852 AK127602 AY262113 AAP33134 AY262114 AAP33135 BC068078 AAH68078 DB262972 XM_011544359 XP_011542661 XM_011544360 XP_011542662 XM_011544361 XP_011542663 XM_011544362 XP_011542664 XM_011544363 XP_011542665 XM_011544364 XP_011542666 NM_001286680 NP_001273609 NM_001286681 NP_001273610 NM_182795 NP_877724 |
Function | Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization. {ECO:0000269|PubMed:21863821}. |
Subcellular Location | Nucleus {ECO:0000250}. Note=Found in the oocyte nucleus before nuclear membrane breakdown, after which it is redistributed to the cytoplasm. {ECO:0000250}. |
NPM2 CRISPR/Cas9 KO Plasmid (h) - sc-411462 from Santa Cruz Biotechnology
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NPM2 HDR Plasmid (h) - sc-411462-HDR from Santa Cruz Biotechnology
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NPM2 Double Nickase Plasmid (h) - sc-411462-NIC from Santa Cruz Biotechnology
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NPM2 Double Nickase Plasmid (h2) - sc-411462-NIC-2 from Santa Cruz Biotechnology
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NPM2 CRISPR Activation Plasmid (h) - sc-411462-ACT from Santa Cruz Biotechnology
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NPM2 CRISPR Activation Plasmid (h2) - sc-411462-ACT-2 from Santa Cruz Biotechnology
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NPM2 Lentiviral Activation Particles (h) - sc-411462-LAC from Santa Cruz Biotechnology
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NPM2 Lentiviral Activation Particles (h2) - sc-411462-LAC-2 from Santa Cruz Biotechnology
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NPM2 siRNA (h) - sc-77504 from Santa Cruz Biotechnology
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NPM2 shRNA Plasmid (h) - sc-77504-SH from Santa Cruz Biotechnology
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NPM2 shRNA (h) Lentiviral Particles - sc-77504-V from Santa Cruz Biotechnology
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Nucleoplasmin-2 RNAi - H00010361-R01 from Novus Biologicals
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MISSION® esiRNA - EHU149901 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15461 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00371 from Sigma-Aldrich
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NPM2 siRNA (Human) - CRH7020 from Cohesion Biosciences
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shRNA set against Human NPM2 (NM_182795.1) - SHH354324 from Creative biogene
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shRNA set against Human NPM2(NM_182795.1) - SHR018534 from Creative biogene
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Human NPM2 siRNA - orb267522 from Biorbyt
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NPM2 shRNA Plasmid (Human) - CHH7020 from Cohesion Biosciences
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NPM2 miRNA 3'UTR clone - MiUTR1H-06878 from Creative biogene
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