GAPDH

Gene Symbol GAPDH
Entrez Gene 493876
Alt Symbol -
Species Cat
Gene Type protein-coding
Description glyceraldehyde-3-phosphate dehydrogenase
Other Description peptidyl-cysteine S-nitrosylase GAPDH
Swissprots Q9N2D5
Accessions Q9N2D5 AB038241 BAA90818 AF054608 AAC15981 AF097177 AAC72840 DQ403061 ABD77194 XM_006933438 XP_006933500 NM_001009307 NP_001009307
Function Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3- phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S- nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in infl
Subcellular Location Cytoplasm, cytosol {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal. {ECO:0000250}.
Top Pathways Glycolysis / Gluconeogenesis, Alzheimer's disease, Biosynthesis of amino acids, Carbon metabolism

Recombinant Cat Glyceraldehyde-3-phosphate dehydrogenase(GAPDH) - CSB-YP009232CA CSB-EP009232CA CSB-BP009232CA CSB-MP009232CA from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), Recombinant Protein - MBS1427934 from MyBioSource

Category Protein
Prices $1,095.00, $1,095.00, $1,325.00, $1,325.00, $1,725.00, $1,725.00, $2,185.00, $2,185.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Cat
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