OSMR

Gene Symbol OSMR
Entrez Gene 9180
Alt Symbol OSMRB, PLCA1
Species Human
Gene Type protein-coding
Description oncostatin M receptor
Other Description IL-31 receptor subunit beta|IL-31R subunit beta|IL-31R-beta|IL-31RB|interleukin-31 receptor subunit beta|oncostatin-M specific receptor beta subunit|oncostatin-M-specific receptor subunit beta
Swissprots Q6P4E8 Q99650 Q96QJ6
Accessions CAL44879 CAL44943 CAL44954 CAP40197 CAV32861 CAX21680 CAX87006 CBL94055 CBX32719 CDM63726 EAW55976 EAW55977 Q99650 AI417125 AK304016 BAG64931 BC010943 AAH10943 BC063468 AAH63468 BC125209 AAI25210 BC125210 AAI25211 BP352496 BU619548 CA439576 CB265977 DR006275 U60805 AAC50946 XM_005248384 XP_005248441 XM_005248385 XP_005248442 XM_005248386 XP_005248443 XM_005248387 XP_005248444 XM_011514161 XP_011512463 XR_925661 NM_001168355 NP_001161827 NM_003999 NP_003990
Function Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events. {ECO:0000269|PubMed:15184896, ECO:0000269|PubMed:8999038}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Expressed at relatively high levels in all neural cells as well as fibroblast, epithelial and a variety of tumor cell lines. {ECO:0000269|PubMed:8999038}.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, PI3K-Akt signaling pathway

OSMR β (AN-A2) - sc-9992 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
OSMR β (AN-A2): sc-9992. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing cytoplasmic and membrane staining of Purkinje cells.

OSMR β (N-20) - sc-8495 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

OSMR β (AN-U2) - sc-21797 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
OSMR β (AN-U2) PE: sc-21797 PE. FCM analysis of HeLa cells. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

OSMR β (H-200) - sc-30010 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
OSMR β (H-200): sc-30010. Western blot analysis of OSMR β expression in HeLa whole cell lysate.

OSMR β (C-20) - sc-8496 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-OSMR antibody - ab172254 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-OSMR antibody (ab172254) at 1 µg/mlLane 1 : OSMR transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgGd at 1/7500 dilution

Anti-OSMR antibody - ab67805 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-OSMR antibody (ab67805) at 1/500 dilutionLane 1 : OSMR transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilutionObserved band size : 50 kDa (why is the actual band size different from the predicted?)

Anti-OSMR antibody - ab156939 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-OSMR antibody (ab156939) at 0.1 µg/ml + HeLa cell lysate at 35 µgdeveloped using the ECL technique

Anti-OSMR / IL-31R-Beta Antibody - LS-C73895 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-OSMR / IL-31R-Beta Antibody (aa28-739, clone 10K58, APC) - LS-C131131 from LifeSpan Bioscience

Prices $590.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 10K58

Anti-OSMR / IL-31R-Beta Antibody (aa513-760, Biotin) - LS-C300418 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-OSMR / IL-31R-Beta Antibody (aa24-738) - LS-C150222 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-OSMR / IL-31R-Beta Antibody (aa503-749, Biotin) - LS-C301073 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-OSMR / IL-31R-Beta Antibody (aa513-760, FITC) - LS-C303271 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-OSMR / IL-31R-Beta Antibody (aa24-738, clone 12K147, PE) - LS-C182921 from LifeSpan Bioscience

Prices $545.00
Sizes 100 tst
Host Rat
Clonality Monoclonal
Clone 12K147

Anti-OSMR / IL-31R-Beta Antibody (aa503-749, FITC) - LS-C303572 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-OSMR / IL-31R-Beta Antibody (clone AN-V2, PE) - LS-C106518 from LifeSpan Bioscience

Prices $245.00, $365.00
Sizes 25 tst, 100 tst
Host Mouse
Clonality Monoclonal
Clone AN-V2
Staining of the Jurkat (left) and A375 (right) cell lines with PE Mouse IgG1, K isotype control (blue histogram) or PE Anti-human oncostatin M receptor (OSMR) (purple histogram). Total viable cells were used for analysis.

Anti-OSMR / IL-31R-Beta Antibody (aa21-70) - LS-C80887 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HT1080 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 8%.

Anti-OSMR / IL-31R-Beta Antibody (clone 30-1) - LS-C179312 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 30-1

Anti-OSMR Antibody (aa513-760) - LS-C295719 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant OSMR.

Anti-OSMR / IL-31R-Beta Antibody (aa503-749) - LS-C295722 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant OSMR.

Anti-OSMR / IL-31R-Beta Antibody - LS-C334872 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using OSMR antibody.

Anti-OSMR / IL-31R-Beta Antibody (aa612-661) IHC-plus™ - LS-B11477 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-OSMR antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11477 concentration 10 ug/ml.

OSM R beta Antibody (118125) [Unconjugated] - MAB662 from Novus Biologicals

Prices $99.00, $259.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 118125

OSM R beta Antibody - AF662 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
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