Gene Symbol | NAA10 |
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Entrez Gene | 8260 |
Alt Symbol | ARD1, ARD1A, ARD1P, DXS707, MCOPS1, NATD, TE2 |
Species | Human |
Gene Type | protein-coding |
Description | N(alpha)-acetyltransferase 10, NatA catalytic subunit |
Other Description | ARD1 homolog A, N-acetyltransferase|N-acetyltransferase ARD1, human homolog of|N-alpha-acetyltransferase 10|N-alpha-acetyltransferase 10, NatA catalytic subunit|N-terminal acetyltransferase complex ARD1 subunit homolog A|natA catalytic subunit Naa10 |
Swissprots | P41227 A6NM98 |
Accessions | EAW72773 EAW72774 EAW72775 EAW72776 P41227 AK294081 BAG57422 AK296593 BAG59209 AK309083 AK315997 BAH14368 AM392552 CAL37430 AM393827 CAL38702 AY183134 AY183135 BC000308 AAH00308 BC019312 AAH19312 BC063377 AAH63377 BI192945 CA313208 CR979270 X77588 CAA54691 NM_001256119 NP_001243048 NM_001256120 NP_001243049 NM_003491 NP_003482 |
Function | Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity. The NAT activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development. {ECO:0000269|PubMed:12464182, ECO:0000269|PubMed:15496142, ECO:0000269|PubMed:19826488, ECO:0000269|PubMed:20145209}. |
Subcellular Location | Cytoplasm. Nucleus. Note=According to PubMed:12464182 it is cytoplasmic. According to PubMed:15496142, it is nuclear and cytoplasmic. Also present in the free cytosolic and cytoskeleton-bound polysomes. |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12464182}. |
Human ARD1A full length protein - ab113135 from Abcam
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NAA10 / ARD1A Antibody Blocking Peptide - LS-E17575 from LifeSpan Bioscience
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NAA10 Recombinant Protein - H00008260-P01 from Novus Biologicals
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Recombinant Human NAA10 Protein - NBP1-72403 from Novus Biologicals
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Human NAA10 protein - orb168883 from Biorbyt
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Human NAA10 protein (GST Tag) - orb139373 from Biorbyt
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ARD1A Blocking Peptide - 33R-9510 from Fitzgerald
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NAA10 protein (His tag) - 80R-1920 from Fitzgerald
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NAA10 / ARD1A (1-235, His-tag) - AR39099PU-L from Acris Antibodies
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NAA10 / ARD1A (1-235, His-tag) - AR39099PU-N from Acris Antibodies
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NAA10 / ARD1A - H00008260-P01-10 from Acris Antibodies
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NAA10 / ARD1A - H00008260-P01-25 from Acris Antibodies
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NAA10, 1-235aa, Human, His tag, E.coli - 01-P1159 from ARP American Research Products
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ARD1A fusion protein - ag7406 from Proteintech Group
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ARD1A fusion protein - Ag6519 from Proteintech Group
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NAA10 Human - ENPS-165 from NeoScientific
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NAA10, 1-235aa, Recombinant Protein - GWB-P0879H from Genway Biotech
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Recombinant Human NAA10, His-tagged - NAA10-3610H from Creative Biomart
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Recombinant Human NAA10, His-tagged - NAA10-26531TH from Creative Biomart
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Recombinant Human NAA10, His-GST tagged - NAA10-8647H from Creative Biomart
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Recombinant Human NAA10, None tagged - NAA10-553H from Creative Biomart
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Human NAA10 / ARD1A Protein (His & GST Tag) - 14293-H20B-20 from Sino Biological
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Human NAA10 / ARD1A Protein - 14293-HNCB-20 from Sino Biological
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Recombinant Human N-alpha-acetyltransferase 10(NAA10) - CSB-YP001984HU CSB-EP001984HU CSB-BP001984HU CSB-MP001984HU from Cusabio
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NAA,10, 1-235aa, Human, His tag, E.coli - ATGP1159 from ATGen
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