CDC5L

Gene Symbol CDC5L
Entrez Gene 988
Alt Symbol CDC5, CDC5-LIKE, CEF1, PCDC5RP, dJ319D22.1
Species Human
Gene Type protein-coding
Description cell division cycle 5-like
Other Description CDC5 cell division cycle 5-like|Cdc5-related protein|cell division cycle 5-like protein|dJ319D22.1 (CDC5-like protein)|pombe cdc5-related protein
Swissprots Q76N46 Q99459 Q99974
Accessions AAR89913 EAX04270 Q99459 AB007892 BAA24862 AK128737 BAG54722 AK299738 BAG61633 BC001568 AAH01568 BG187521 BG497404 BM829346 D85423 BAA20885 DC422730 DQ891623 ABM82549 DQ894814 ABM85740 U86753 AAB61210 XM_006715289 XP_006715352 XR_926346 NM_001253 NP_001244
Function DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). {ECO:0000269|PubMed:10570151, ECO:0000269|PubMed:11082045, ECO:0000269|PubMed:11101529, ECO:0000269|PubMed:11544257, ECO:0000269|PubMed:12927788, ECO:0000269|PubMed:18583928, ECO:0000269|PubMed:24332808, ECO:0000269|PubMed:9038199, ECO:0000269|PubMed:9468527, ECO:0000269|PubMed:9632794}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10570151, ECO:0000269|PubMed:11544257, ECO:0000269|PubMed:18583928, ECO:0000269|PubMed:9038199, ECO:0000269|PubMed:9598309}. Nucleus speckle {ECO:0000269|PubMed:10570151, ECO:0000269|PubMed:10827081, ECO:0000269|PubMed:11544257}. Cytoplasm {ECO:0000269|PubMed:9038199}. Note=May shuttle between cytoplasm and nucleus. {ECO:0000269|PubMed:9038199}.
Tissue Specificity Ubiquitously expressed in both fetal and adult tissues. {ECO:0000269|PubMed:9038199, ECO:0000269|PubMed:9598309, ECO:0000269|PubMed:9632794}.
Top Pathways Spliceosome

Human CDC5L full length protein - ab132350 from Abcam

Category Protein
Prices $402.00
Sizes 2 µg
Source Wheat germ
Species Human
12.5% SDS-PAGE analysis of ab132350 stained with Coomassie Blue.

Human CDC5L peptide - ab30674 from Abcam

Category Peptide
Prices $181.00
Sizes 100 µg

Human CDC5L protein fragment - ab158071 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
ab158071 on a 12.5% SDS-PAGE stained with Coomassie Blue.

CDC5 / CDC5L Antibody Blocking Peptide - LS-E14701 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CDC5 / CDC5L Antibody Blocking Peptide - LS-E9868 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human CDC5L Protein - H00000988-P01 from Novus Biologicals

Category Protein
Prices $250.00
Sizes 2 µg
Source Wheat Germ
Species Human

Recombinant Human CDC5L Protein - H00000988-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

CDC5L-Antibody-Center-Blocking-Peptide - BP8949c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CDC5L Blocking Peptide - 33R-5034 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

CDC5L - H00000988-P01 from Acris Antibodies

Category Protein
Prices $340.00
Sizes 2 µg
Species Human

CDC5L - H00000988-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

CDC5L - H00000988-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

CDC5L fusion protein - Ag3578 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human CDC5L, GST-tagged - CDC5L-11017H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Cell division cycle 5-like protein(CDC5L) ,partial - CSB-YP858712HU CSB-EP858712HU CSB-BP858712HU CSB-MP858712HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CDC5L - TP301702 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
CDC5L

Cell division cycle 5-like protein (CDC5L), partial, Recombinant Protein - MBS1434047 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

CDC5L Recombinant Protein Antigen - NBP1-85720PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

CDC5L Recombinant Protein Antigen - NBP1-85719PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

CDC5L Peptide, Human - M34GP02817H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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