| Gene Symbol |
MAPRE3
|
| Entrez Gene |
22924
|
| Alt Symbol |
EB3, EBF3, EBF3-S, RP3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
microtubule-associated protein, RP/EB family, member 3
|
| Other Description |
APC binding protein|EB1 protein family member 3|end-binding protein 3|microtubule-associated protein RP/EB family member 3
|
| Swissprots |
Q9UPY8 Q9BZP7 Q6FHB0 Q6FI15 O00265 B7WPK5 Q9BZP8
|
| Accessions |
AAK07556 AAK07557 AAY14653 EAX00660 EAX00661 EAX00662 EAX00663 EAX00664 EAX00665 EAX00666 Q9UPY8 AB025186 BAA82958 AK302950 BAH13853 AK312342 BAG35263 BC011557 AAH11557 BM560331 CR536523 CAG38760 CR541845 CAG46643 DC417465 DQ892305 ABM83231 DQ895504 ABM86430 HY011071 Y11174 CAA72060 XM_006711967 XP_006712030 XM_011532700 XP_011531002 NM_001303050 NP_001289979 NM_012326 NP_036458
|
| Function |
Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10644998, ECO:0000269|PubMed:19255245}. Note=Associated with the microtubule network. Detected at the plus end of microtubules.
|
| Tissue Specificity |
Predominantly expressed in brain and muscle. {ECO:0000269|PubMed:10644998}.
|
![Western Blot: EB3 Overexpression Lysate (Adult Normal) [NBL1-12893] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for EB3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6147_EB3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12893-img0002.jpg)