Gene Symbol | MAPRE3 |
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Entrez Gene | 22924 |
Alt Symbol | EB3, EBF3, EBF3-S, RP3 |
Species | Human |
Gene Type | protein-coding |
Description | microtubule-associated protein, RP/EB family, member 3 |
Other Description | APC binding protein|EB1 protein family member 3|end-binding protein 3|microtubule-associated protein RP/EB family member 3 |
Swissprots | Q9UPY8 Q9BZP7 Q6FHB0 Q6FI15 O00265 B7WPK5 Q9BZP8 |
Accessions | AAK07556 AAK07557 AAY14653 EAX00660 EAX00661 EAX00662 EAX00663 EAX00664 EAX00665 EAX00666 Q9UPY8 AB025186 BAA82958 AK302950 BAH13853 AK312342 BAG35263 BC011557 AAH11557 BM560331 CR536523 CAG38760 CR541845 CAG46643 DC417465 DQ892305 ABM83231 DQ895504 ABM86430 HY011071 Y11174 CAA72060 XM_006711967 XP_006712030 XM_011532700 XP_011531002 NM_001303050 NP_001289979 NM_012326 NP_036458 |
Function | Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10644998, ECO:0000269|PubMed:19255245}. Note=Associated with the microtubule network. Detected at the plus end of microtubules. |
Tissue Specificity | Predominantly expressed in brain and muscle. {ECO:0000269|PubMed:10644998}. |
EB3 CRISPR/Cas9 KO Plasmid (h) - sc-406026 from Santa Cruz Biotechnology
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EB3 HDR Plasmid (h) - sc-406026-HDR from Santa Cruz Biotechnology
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EB3 Double Nickase Plasmid (h) - sc-406026-NIC from Santa Cruz Biotechnology
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EB3 Double Nickase Plasmid (h2) - sc-406026-NIC-2 from Santa Cruz Biotechnology
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EB3 CRISPR Activation Plasmid (h) - sc-406026-ACT from Santa Cruz Biotechnology
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EB3 CRISPR Activation Plasmid (h2) - sc-406026-ACT-2 from Santa Cruz Biotechnology
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EB3 Lentiviral Activation Particles (h) - sc-406026-LAC from Santa Cruz Biotechnology
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EB3 Lentiviral Activation Particles (h2) - sc-406026-LAC-2 from Santa Cruz Biotechnology
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EB3 siRNA (h) - sc-37608 from Santa Cruz Biotechnology
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EB3 shRNA Plasmid (h) - sc-37608-SH from Santa Cruz Biotechnology
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EB3 shRNA (h) Lentiviral Particles - sc-37608-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU011851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13027 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13027 from Sigma-Aldrich
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MAPRE3 siRNA (Human) - CRH7875 from Cohesion Biosciences
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shRNA set against Human MAPRE3 (NM_012326.2) - SHH338215 from Creative biogene
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shRNA set against Human MAPRE3(NM_012326.2) - SHH176771 from Creative biogene
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Human MAPRE3 siRNA - orb268377 from Biorbyt
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MAPRE3 shRNA Plasmid (Human) - CHH7875 from Cohesion Biosciences
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MAPRE3 miRNA 3'UTR clone - MiUTR1H-06105 from Creative biogene
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