TUBB3

Gene Symbol TUBB3
Entrez Gene 10381
Alt Symbol CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4
Species Human
Gene Type protein-coding
Description tubulin, beta 3 class III
Other Description class III beta-tubulin|tubulin beta-3 chain|tubulin beta-4 chain|tubulin beta-III
Swissprots Q9BTZ0 A8K854 Q9BW10 Q13509
Accessions EAW66669 EAW66674 EAW66675 Q13509 AF427491 AAL28094 AK058140 AK122757 BAG53710 AK127418 AK223039 BAD96759 AK292219 BAF84908 AK307201 AK314616 BAG37182 AU142509 BC000748 AAH00748 BC001678 AAH01678 BC003021 AAH03021 BC047518 AAH47518 BC064975 CD621827 DA054466 S62643 U47634 AAC52035 NM_001197181 NP_001184110 NM_006086 NP_006077
Function Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance. {ECO:0000269|PubMed:20074521}.
Subcellular Location Cytoplasm, cytoskeleton.
Tissue Specificity Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues. {ECO:0000269|PubMed:14736079, ECO:0000269|PubMed:20191564}.
Top Pathways Gap junction, Pathogenic Escherichia coli infection, Phagosome

β3 Tubulin CRISPR/Cas9 KO Plasmid (h) - sc-400525 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

β3 Tubulin HDR Plasmid (h) - sc-400525-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

β3 Tubulin Double Nickase Plasmid (h) - sc-400525-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

β3 Tubulin Double Nickase Plasmid (h2) - sc-400525-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

β3 Tubulin CRISPR Activation Plasmid (h) - sc-400525-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

β3 Tubulin CRISPR Activation Plasmid (h2) - sc-400525-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

β3 Tubulin Lentiviral Activation Particles (h) - sc-400525-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

β3 Tubulin Lentiviral Activation Particles (h2) - sc-400525-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

β3 Tubulin siRNA (h) - sc-105009 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

β3 Tubulin shRNA Plasmid (h) - sc-105009-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

β3 Tubulin shRNA (h) Lentiviral Particles - sc-105009-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

beta-III Tubulin RNAi - H00010381-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU153211 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1960 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1960 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02443 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr02443

TUBB3 siRNA (Human) - CRH7032 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TUBB3 - MBS8207645 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TUBB3 shRNA Plasmid (Human) - CHH7032 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TUBB3 miRNA 3'UTR clone - MiUTR3H-05198 from Creative biogene

Species Reactivities Human
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