MMP8

Gene Symbol MMP8
Entrez Gene 4317
Alt Symbol CLG1, HNC, MMP-8, PMNL-CL
Species Human
Gene Type protein-coding
Description matrix metallopeptidase 8
Other Description PMN leukocyte collagenase|PMNL collagenase|collagenase 2|matrix metalloproteinase 8 (neutrophil collagenase)|matrix metalloproteinase-8|neutrophil collagenase
Swissprots Q45F99 P22894
Accessions AAZ38714 EAW67027 P22894 AK292659 BAF85348 AK303388 BAG64444 AK303511 BAG64542 AK313374 AL597614 AW468376 BC074988 AAH74988 BC074989 AAH74989 BC144094 BG213446 BG218770 DW009698 J05556 AAA88021 XM_011542834 XP_011541136 XM_011542835 XP_011541137 XM_011542836 XP_011541138 NM_001304441 NP_001291370 NM_001304442 NP_001291371 NM_002424 NP_002415
Function Can degrade fibrillar type I, II, and III collagens.
Subcellular Location Cytoplasmic granule. Secreted, extracellular space, extracellular matrix {ECO:0000305}. Note=Stored in intracellular granules.
Tissue Specificity Neutrophils.

MMP-8 (H-45) - sc-50383 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MMP-8 (H-45): sc-50383. Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing cytoplasmic staining of cells in white pulp and cells in red pulp.

MMP-8 (M-20) - sc-8848 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MMP-8 (M-20): sc-8848. Western blot analysis of MMP-8 expression in SJRH30 whole cell lysate.

MMP-8 (M-16) - sc-31741 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MMP-8 (C-20) - sc-8849 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MMP-8 (C-20): sc-8849. Western blot analysis of MMP-8 expression in SJRH30 whole cell lysate.

MMP-8 (MM0023-7A11) - sc-101450 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-MMP8 antibody - ab53017 from Abcam

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP8 antibody (ab53017) at 1/500 dilutionLane 1 : Extracts from NIH/3T3 cells with no immunizing peptideLane 2 : Extracts from NIH/3T3 cells with immunizing peptide

Anti-MMP8 antibody - ab78423 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab78423 at 1µg/ml staining MMP8 in rat lung tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections). A Biotin-conjugated Goat anti-rabbit IgG was used as secondary at 1/200 dilution.

Anti-MMP8 antibody - ab154507 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MMP8 antibody (ab154507) at 1/10000 dilution + HCT116 whole cell lysate at 30 µg

Anti-MMP8 antibody - ab189063 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labeling MMP8 with ab189063 at 10 µg/ml.

Anti-MMP8 antibody - ab38988 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab38988 stained Hek293 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab38988, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-MMP8 antibody - ab38994 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Standard curve for MMP8; dilution range 1pg/ml to 1µg/ml using Capture Antibody Mouse monoclonal [MM0023-7A11] to MMP8 (ab56303) at 5µg/ml and Detector Antibody Rabbit polyclonal to MMP8 - Hinge region (ab38994) at 0.5µg/ml.

Anti-MMP8 antibody - ab72897 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP8 antibody (ab72897) at 1 µg/mlLane 1 : Bone Marrow (Human) Tissue Lysate - adult normal tissue Lane 2 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 3 : Skin (Human) Tissue Lysate - adult normal tissue (ab30166)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-MMP8 antibody - ab89834 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP8 antibody (ab89834) at 1 µg/mlLane 1 : Lung (Human) Tissue LysateLane 2 : Testis (Human) Tissue Lysate - adult normal tissue (ab30257)Lane 3 : Ovary (Human) Tissue Lysate - adult normal tissue (ab30222)Lane 4 : MOLT4 (Human acute lymphoblastic leukemia cell line) Whole Cell Lysate Lane 5 :  Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLane 6 : Raji (Human Burkitt's lymphoma cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-MMP8 antibody [EP1252Y] - ab81286 from Abcam

Prices $391.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1252Y
Anti-MMP8 antibody [EP1252Y] (ab81286) at 1/2000 dilution + Rat lung lysate at 10 µgSecondaryHRP conjugated goat anti-rabbit at 1/2000 dilution

Anti-MMP8 antibody [MM0023-7A11] - ab56303 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0023-7A11
Standard curve for MMP8; dilution range 1pg/ml to 1µg/ml using Capture Antibody Mouse monoclonal [MM0023-7A11] to MMP8 (ab56303) at 5µg/ml and Detector Antibody Rabbit polyclonal to MMP8 - Hinge region (ab38994) at 0.5µg/ml.

Anti-MMP8 antibody - Aminoterminal end - ab38992 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP8 antibody - C-terminal - ab157170 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-MMP8 antibody - C-terminal (ab157170) at 1/1000 dilutionLane 1 : Mouse thymus total cell extractLane 2 : HepG2 total cell extract

Anti-MMP8 antibody - Carboxyterminal end - ab38990 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP8 Antibody (aa301-315) - LS-C3138 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP8 Antibody (clone 115–13D2) - LS-C8779 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 115–13D2

Anti-MMP8 Antibody (N-Terminus) - LS-C122100 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP8 Antibody - LS-C72201 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MMP8 Antibody - LS-C48494 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP8 Antibody (aa103-115) - LS-C124061 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MMP8 Antibody (C-Terminus) - LS-C124060 from LifeSpan Bioscience

Prices $620.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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