Gene Symbol | MMP8 |
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Entrez Gene | 4317 |
Alt Symbol | CLG1, HNC, MMP-8, PMNL-CL |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 8 |
Other Description | PMN leukocyte collagenase|PMNL collagenase|collagenase 2|matrix metalloproteinase 8 (neutrophil collagenase)|matrix metalloproteinase-8|neutrophil collagenase |
Swissprots | Q45F99 P22894 |
Accessions | AAZ38714 EAW67027 P22894 AK292659 BAF85348 AK303388 BAG64444 AK303511 BAG64542 AK313374 AL597614 AW468376 BC074988 AAH74988 BC074989 AAH74989 BC144094 BG213446 BG218770 DW009698 J05556 AAA88021 XM_011542834 XP_011541136 XM_011542835 XP_011541137 XM_011542836 XP_011541138 NM_001304441 NP_001291370 NM_001304442 NP_001291371 NM_002424 NP_002415 |
Function | Can degrade fibrillar type I, II, and III collagens. |
Subcellular Location | Cytoplasmic granule. Secreted, extracellular space, extracellular matrix {ECO:0000305}. Note=Stored in intracellular granules. |
Tissue Specificity | Neutrophils. |
MMP-8 CRISPR/Cas9 KO Plasmid (h) - sc-402089 from Santa Cruz Biotechnology
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MMP-8 HDR Plasmid (h) - sc-402089-HDR from Santa Cruz Biotechnology
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MMP-8 Double Nickase Plasmid (h) - sc-402089-NIC from Santa Cruz Biotechnology
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MMP-8 Double Nickase Plasmid (h2) - sc-402089-NIC-2 from Santa Cruz Biotechnology
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MMP-8 CRISPR Activation Plasmid (h) - sc-402089-ACT from Santa Cruz Biotechnology
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MMP-8 CRISPR Activation Plasmid (h2) - sc-402089-ACT-2 from Santa Cruz Biotechnology
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MMP-8 Lentiviral Activation Particles (h) - sc-402089-LAC from Santa Cruz Biotechnology
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MMP-8 Lentiviral Activation Particles (h2) - sc-402089-LAC-2 from Santa Cruz Biotechnology
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MMP-8 siRNA (h) - sc-35949 from Santa Cruz Biotechnology
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MMP-8 shRNA Plasmid (h) - sc-35949-SH from Santa Cruz Biotechnology
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MMP-8 shRNA (h) Lentiviral Particles - sc-35949-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU047031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2081 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06258 from Sigma-Aldrich
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MMP8 siRNA (Human) - CRH2929 from Cohesion Biosciences
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MMP-8 RNAi - H00004317-R01 from Novus Biologicals
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shRNA set against Human MMP8 (NM_002424.2) - SHH343120 from Creative biogene
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MMP8 shRNA Plasmid (Human) - CHH2929 from Cohesion Biosciences
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MMP8 miRNA 3'UTR clone - MiUTR3H-00497 from Creative biogene
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