ING1

Gene Symbol ING1
Entrez Gene 3621
Alt Symbol p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
Species Human
Gene Type protein-coding
Description inhibitor of growth family, member 1
Other Description growth inhibitor ING1|growth inhibitory protein ING1|inhibitor of growth protein 1|tumor suppressor ING1
Swissprots Q9UIJ3 Q9UBC6 Q9UIJ4 Q5T9H1 Q9UK52 Q9NS83 O43658 Q5T9G8 O00532 Q9UIJ2 Q9HD98 Q9P0U6 Q5T9G9 Q9HD99 Q9UIJ1 Q5T9H0 Q53ZR3 Q9H007 Q9UK53
Accessions AAG02578 AAG02579 AAG12175 BAA82888 BAA82889 BAA82890 BAA83462 BAB08101 BAB08102 BAB08103 CBX53821 CBX53822 CBX53823 CBX53824 EAX09127 EAX09128 EAX09129 EAX09130 EAX09131 Q9UK53 AA450055 AB024401 BAA82886 AB024402 BAA82887 AB031269 BAA83496 AB037594 BAB20992 AF001954 AAB60879 AF044076 AAC00501 AF078835 AAG12174 AF149721 AAF37421 AF149722 AAF37422 AF149723 AAF37423 AF181849 AAF07920 AF181850 AAF07921 AI016573 AJ310392 CAC38067 AK302353 BAG63679 BC018348 BC093942 AAH93942 BC093944 AAH93944 BF435293 BF510437 BG703874 BQ430264 DB450867 DB537640 NM_001267728 NP_001254657 NM_005537 NP_005528 NM_198217 NP_937860 NM_198218 NP_937861 NM_198219 NP_937862
Function Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene. {ECO:0000269|PubMed:9440695}.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Isoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines. {ECO:0000269|PubMed:10626813}.

ING1b (D3D5Z) Rabbit mAb - 14625 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3D5Z
Western blot analysis of extracts from various cell lines using ING1b (D3D5Z) Rabbit mAb.

ING1 (C-19) - sc-7566 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ING1 (C-19): sc-7566. Western blot analysis of ING1 expression in HeLa (A), A-673 (B), Jurkat (C), K-562 (D), MOLT-4 (E) and CCRF-CEM (F) nuclear extracts.

ING1 (E-10) - sc-373817 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ING1 (E-10): sc-373817. Western blot analysis of ING1 expression in non-transfected: sc-117752 (A) and mouse ING1 transfected: sc-122316 (B) 293T whole cell lysates and K-562 nuclear extract (C).

ING1 (E-2) - sc-374295 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ING1 (E-2): sc-374295. Western blot analysis of ING1 expression in non-transfected: sc-117752 (A) and mouse ING1 transfected: sc-122316 (B) 293T whole cell lysates.

ING1 (H-220) - sc-67325 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ING1 (H-220): sc-67325. Western blot analysis of ING1 expression in mouse brain tissue extract.

ING1 (H-80) - sc-28227 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ING1 (H-80): sc-28227. Western blot analysis of ING1 expression in non-transfected: sc-117752 (A) and mouse ING1 transfected: sc-122316 (B) 293T whole cell lysates.

p47ING1 (N-19) - sc-7567 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p47ING1 (N-19): sc-7567. Western blot analysis of p47ING1 expression in HeLa (A), A-673 (B) and K-562 (C) nuclear extracts.

p47ING1 (N-14) - sc-55238 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

p47ING1 (G-15) - sc-55237 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

p33ING1 (CAb 9) - sc-21729 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
p33ING1 (CAb 9): sc-21729. Western blot analysis of p33ING1 expression in IMR-32 nuclear extract.

p33ING1 (CAb 3) - sc-21728 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
p33ING1 (CAb 3): sc-21728. Western blot analysis of p33ING1 expression in IMR-32 nuclear extract.

Anti-ING1 (phospho S126) antibody - ab77896 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ING1 antibody - ab22664 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ING1 antibody (ab22664) at 1 µg/mlLane 1 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 2 : HCT 116 (Human Colorectal Carcinoma) Whole Cell LysateLane 3 : MCF7 (Human breast adenocarcinoma cell line) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Anti-ING1 antibody - ab169277 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Immunofluorescence analysis of HeLa cells, labeling ING1 with purified ab169277 at 10&microg/ml. Antibody purification with Protein A will be needed prior to use.

Anti-ING1 antibody - ab55306 from Abcam

Host Mouse
Clonality Monoclonal

Anti-ING1 antibody (Biotin) - Aminoterminal end - ab55883 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ING1 antibody [EPR6788] - ab124893 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6788
All lanes : Anti-ING1 antibody [EPR6788] (ab124893) at 1/1000 dilutionLane 1 : HepG2 lysateLane 2 : HeLa lysateLane 3 : MCF-7 lysateLane 4 : Jurkat lysateLane 5 : C6 lysateLane 6 : RAW 264.7 lysateLane 7 : PC-12 lysateLane 8 : NIH/3T3 lysateLysates/proteins at 10 µg per lane.

Anti-ING1 antibody (HRP) - ab28556 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ING1 antibody [MM0770-42J35] - ab201597 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0770-42J35

Anti-ING1 antibody - N-terminal - ab197978 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ING1 antibody - N-terminal (ab197978) at 1/267 dilutionLane 1 : HeLa cell lysateLane 2 : Mouse brain tissue lysateLane 3 : Jurkat cell lysateLane 4 : RAW 264.7 cell lysateLysates/proteins at 40 µg per lane.

Anti-ING1 Antibody (aa70-279) - LS-C7487 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-ING1 Antibody (N-Terminus) - LS-C7488 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ING1 Antibody - LS-C7489 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-ING1 Antibody (N-Terminus) - LS-C36884 from LifeSpan Bioscience

Prices $445.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti-ING1 Antibody (aa285-296) - LS-C70697 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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