| Gene Symbol |
ABCC10
|
| Entrez Gene |
89845
|
| Alt Symbol |
EST182763, MRP7, SIMRP7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
|
| Other Description |
ATP-binding cassette sub-family C member 10|multidrug resistance-associated protein 7
|
| Swissprots |
Q5T3U5 Q9UF48 Q9H7N2 Q9NXY3 Q8NHX7
|
| Accessions |
EAX04180 EAX04181 EAX04182 EAX04183 EAX04184 EAX04185 Q5T3U5 AK000002 BAA92227 AK024446 BAB15736 AL122095 CAB59263 AL133613 CAB63742 AY032599 AAK39642 BC024103 AAH24103 BC166699 AAI66699 XM_011514974 XP_011513276 XM_011514975 XP_011513277 XM_011514976 XP_011513278 XM_011514977 XP_011513279 XM_011514978 XP_011513280 XM_011514979 XP_011513281 XM_011514980 XP_011513282 XM_011514981 XP_011513283 XM_011514982 XP_011513284 XM_011514983 XP_011513285 XM_011514984 XP_011513286 XM_011514985 XP_011513287 XM_011514986 XP_011513288 XR_926334 XR_926335 NM_001198934 NP_001185863 NM_033450 NP_258261
|
| Function |
ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. {ECO:0000269|PubMed:12527806, ECO:0000269|PubMed:15256465}.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:12566991, ECO:0000269|PubMed:15256465}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:12566991, ECO:0000269|PubMed:15256465}.
|
| Tissue Specificity |
Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed. {ECO:0000269|PubMed:12566991}.
|
| Top Pathways |
ABC transporters
|