Gene Symbol | ABCC10 |
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Entrez Gene | 89845 |
Alt Symbol | EST182763, MRP7, SIMRP7 |
Species | Human |
Gene Type | protein-coding |
Description | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 |
Other Description | ATP-binding cassette sub-family C member 10|multidrug resistance-associated protein 7 |
Swissprots | Q5T3U5 Q9UF48 Q9H7N2 Q9NXY3 Q8NHX7 |
Accessions | EAX04180 EAX04181 EAX04182 EAX04183 EAX04184 EAX04185 Q5T3U5 AK000002 BAA92227 AK024446 BAB15736 AL122095 CAB59263 AL133613 CAB63742 AY032599 AAK39642 BC024103 AAH24103 BC166699 AAI66699 XM_011514974 XP_011513276 XM_011514975 XP_011513277 XM_011514976 XP_011513278 XM_011514977 XP_011513279 XM_011514978 XP_011513280 XM_011514979 XP_011513281 XM_011514980 XP_011513282 XM_011514981 XP_011513283 XM_011514982 XP_011513284 XM_011514983 XP_011513285 XM_011514984 XP_011513286 XM_011514985 XP_011513287 XM_011514986 XP_011513288 XR_926334 XR_926335 NM_001198934 NP_001185863 NM_033450 NP_258261 |
Function | ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion. {ECO:0000269|PubMed:12527806, ECO:0000269|PubMed:15256465}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:12566991, ECO:0000269|PubMed:15256465}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:12566991, ECO:0000269|PubMed:15256465}. |
Tissue Specificity | Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed. {ECO:0000269|PubMed:12566991}. |
Top Pathways | ABC transporters |
MRP7 CRISPR/Cas9 KO Plasmid (h) - sc-406412 from Santa Cruz Biotechnology
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MRP7 HDR Plasmid (h) - sc-406412-HDR from Santa Cruz Biotechnology
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MRP7 Double Nickase Plasmid (h) - sc-406412-NIC from Santa Cruz Biotechnology
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MRP7 Double Nickase Plasmid (h2) - sc-406412-NIC-2 from Santa Cruz Biotechnology
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MRP7 CRISPR Activation Plasmid (h) - sc-406412-ACT from Santa Cruz Biotechnology
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MRP7 CRISPR Activation Plasmid (h2) - sc-406412-ACT-2 from Santa Cruz Biotechnology
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MRP7 Lentiviral Activation Particles (h) - sc-406412-LAC from Santa Cruz Biotechnology
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MRP7 Lentiviral Activation Particles (h2) - sc-406412-LAC-2 from Santa Cruz Biotechnology
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MRP7 siRNA (h) - sc-62641 from Santa Cruz Biotechnology
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MRP7 shRNA Plasmid (h) - sc-62641-SH from Santa Cruz Biotechnology
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MRP7 shRNA (h) Lentiviral Particles - sc-62641-V from Santa Cruz Biotechnology
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ABCC10 RNAi - H00089845-R02 from Novus Biologicals
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MISSION® esiRNA - EHU064751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2634 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2634 from Sigma-Aldrich
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ABCC10 siRNA (Human) - CRJ3865 from Cohesion Biosciences
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ABCC10 - MBS828908 from MyBioSource
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shRNA set against Human ABCC10 (NM_033450.2) - SHH229082 from Creative biogene
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shRNA set against Human ABCC10(NM_033450.2) - SHG023941 from Creative biogene
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Human ABCC10 siRNA - orb274366 from Biorbyt
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ABCC10 shRNA Plasmid (Human) - CHJ3865 from Cohesion Biosciences
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ABCC10 miRNA 3'UTR clone - MiUTR1H-00036 from Creative biogene
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