| Gene Symbol |
FRMD7
|
| Entrez Gene |
90167
|
| Alt Symbol |
NYS, NYS1, XIPAN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
FERM domain containing 7
|
| Other Description |
FERM domain-containing protein 7
|
| Swissprots |
C0LLJ3 Q6ZUT3 Q5JX99
|
| Accessions |
EAX11785 Q6ZUT3 AI492387 AK125336 BAC86135 AL161984 BC114371 AAI14372 DB511321 FJ717411 ACN56448 XM_005262493 XP_005262550 NM_001306193 NP_001293122 NM_194277 NP_919253
|
| Function |
Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability. {ECO:0000250|UniProtKB:A2AD83, ECO:0000269|PubMed:17013395, ECO:0000269|PubMed:23946638}.
|
| Subcellular Location |
Cell projection {ECO:0000250|UniProtKB:A2AD83}. Cell projection, growth cone {ECO:0000250|UniProtKB:A2AD83}. Note=In undifferentiated neurons, located in the actin-rich regions of the cell body. In differentiated neurons, located in the actin-rich regions of the cell body and primary neurite processes but is almost absent from secondary extensions arising from the primary neurite. Also found at the actin-rich distal end of growth cones (By similarity). {ECO:0000250|UniProtKB:A2AD83}.
|
| Tissue Specificity |
Expressed in liver, kidney, pancreas and at low levels in brain and heart. Expressed in embryonic brain and developing neural retina. {ECO:0000269|PubMed:17013395}.
|
![Western Blot: FRMD7 Overexpression Lysate (Adult Normal) [NBP2-04753] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for FRMD7.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4152_FRMD7%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04753-img0001.jpg)