Gcnt1

Gene Symbol Gcnt1
Entrez Gene 14537
Alt Symbol 5630400D21Rik, B130048E03, C2 GlcNAcT, C2GNT, IGnT
Species Mouse
Gene Type protein-coding
Description glucosaminyl (N-acetyl) transferase 1, core 2
Other Description beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase|beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (Core 2 branching enzyme) (Core2-GlcNAc-transferase) (C2GNT)|core 2-branching enzyme|core2-GlcNAc-transferase
Swissprots Q8BRB2 O35981 Q09324
Accessions Q09324 AK017462 AK045216 BAC32265 AK167048 AK199888 BC039126 AAH39126 BP762673 BY010642 BY431975 BY768580 CJ092264 D87332 BAA22998 D87333 BAA22999 U19265 AAA60948 XM_006526679 XP_006526742 XM_011247144 XP_011245446 NM_001136484 NP_001129956 NM_010265 NP_034395 NM_173442 NP_775618
Function Glycosyltransferase that catalyzes the transfer of an N- acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O- glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes. {ECO:0000269|PubMed:7983056}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Also detected in the trans-Golgi network. {ECO:0000250}.
Tissue Specificity Expressed in kidney, liver, stomach, spleen, lung and brain. {ECO:0000269|PubMed:9341170}.
Top Pathways Mucin type O-Glycan biosynthesis

GCNT1 CRISPR/Cas9 KO Plasmid (m) - sc-420514 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GCNT1 HDR Plasmid (m) - sc-420514-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GCNT1 Double Nickase Plasmid (m) - sc-420514-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GCNT1 Double Nickase Plasmid (m2) - sc-420514-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GCNT1 CRISPR Activation Plasmid (m) - sc-420514-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GCNT1 CRISPR Activation Plasmid (m2) - sc-420514-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GCNT1 Lentiviral Activation Particles (m) - sc-420514-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GCNT1 Lentiviral Activation Particles (m2) - sc-420514-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

GCNT1 siRNA (m) - sc-145363 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

GCNT1 shRNA Plasmid (m) - sc-145363-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

GCNT1 shRNA (m) Lentiviral Particles - sc-145363-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

MISSION® esiRNA - EMU214001 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN31796 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31796 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GCNT1 siRNA (Mouse) - CRM1520 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

GCNT1 - MBS829261 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

Mouse GCNT1 siRNA - orb280996 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

GCNT1 shRNA Plasmid (Mouse) - CHM1520 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse
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