| Gene Symbol |
CDC42EP5
|
| Entrez Gene |
148170
|
| Alt Symbol |
Borg3, CEP5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CDC42 effector protein (Rho GTPase binding) 5
|
| Other Description |
binder of Rho GTPases 3|cdc42 effector protein 5
|
| Swissprots |
B0VJZ2 Q8TB51 Q6NZY7
|
| Accessions |
EAW72252 Q6NZY7 AI379873 BC024327 AAH24327 BC065910 AAH65910 DA867588 NM_145057 NP_659494
|
| Function |
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endomembrane system {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
|