Gene Symbol | CDC42EP5 |
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Entrez Gene | 148170 |
Alt Symbol | Borg3, CEP5 |
Species | Human |
Gene Type | protein-coding |
Description | CDC42 effector protein (Rho GTPase binding) 5 |
Other Description | binder of Rho GTPases 3|cdc42 effector protein 5 |
Swissprots | B0VJZ2 Q8TB51 Q6NZY7 |
Accessions | EAW72252 Q6NZY7 AI379873 BC024327 AAH24327 BC065910 AAH65910 DA867588 NM_145057 NP_659494 |
Function | Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42 (By similarity). {ECO:0000250}. |
Subcellular Location | Endomembrane system {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. |
Cdc42EP5 CRISPR/Cas9 KO Plasmid (h) - sc-408551 from Santa Cruz Biotechnology
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Cdc42EP5 HDR Plasmid (h) - sc-408551-HDR from Santa Cruz Biotechnology
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Cdc42EP5 Double Nickase Plasmid (h) - sc-408551-NIC from Santa Cruz Biotechnology
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Cdc42EP5 Double Nickase Plasmid (h2) - sc-408551-NIC-2 from Santa Cruz Biotechnology
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Cdc42EP5 CRISPR Activation Plasmid (h) - sc-408551-ACT from Santa Cruz Biotechnology
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Cdc42EP5 CRISPR Activation Plasmid (h2) - sc-408551-ACT-2 from Santa Cruz Biotechnology
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Cdc42EP5 Lentiviral Activation Particles (h) - sc-408551-LAC from Santa Cruz Biotechnology
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Cdc42EP5 Lentiviral Activation Particles (h2) - sc-408551-LAC-2 from Santa Cruz Biotechnology
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Cdc42EP5 siRNA (h) - sc-97416 from Santa Cruz Biotechnology
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Cdc42EP5 shRNA Plasmid (h) - sc-97416-SH from Santa Cruz Biotechnology
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Cdc42EP5 shRNA (h) Lentiviral Particles - sc-97416-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN5790 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5790 from Sigma-Aldrich
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CDC42EP5 siRNA (Human) - CRJ5568 from Cohesion Biosciences
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CDC42EP5 - MBS8211269 from MyBioSource
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shRNA set against Human CDC42EP5 (NM_145057.2) - SHH259905 from Creative biogene
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shRNA set against Human CDC42EP5(NM_145057.2) - SHG161845 from Creative biogene
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Human CDC42EP5 siRNA - orb276069 from Biorbyt
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CDC42EP5 shRNA Plasmid (Human) - CHJ5568 from Cohesion Biosciences
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CDC42EP5 miRNA 3'UTR clone - MiUTR3H-10445 from Creative biogene
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