ZMYND11

Gene Symbol ZMYND11
Entrez Gene 10771
Alt Symbol BRAM1, BS69, MRD30
Species Human
Gene Type protein-coding
Description zinc finger, MYND-type containing 11
Other Description adenovirus 5 E1A-binding protein|bone morphogenetic protein receptor-associated molecule 1|zinc finger MYND domain-containing protein 11
Swissprots Q2LD47 Q15326 Q8N4B3 Q2LD48 Q5VUI1 B7Z293 B2R6G8 Q2LD45 F6UH50 Q2LD46
Accessions EAW86539 EAW86540 EAW86541 EAW86542 Q15326 AI031881 AI244299 AK294469 BAH11779 AK294781 BAH11882 AK296427 BAH12348 AK296518 BAH12377 AK312570 BAG35465 AY732489 AAV33128 BC012586 AAH12586 BC034784 AAH34784 BC091489 AAH91489 BP873033 BU680177 CB241408 CF137216 DB236591 DB521520 DC376390 DQ335452 ABC72408 DQ335453 ABC72409 DQ335454 ABC72410 DQ335455 ABC72411 DQ891317 ABM82243 DQ894501 ABM85427 X86098 CAA60052 XM_005252359 XP_005252416 XM_005252360 XP_005252417 XM_005252361 XP_005252418 XM_005252362 XP_005252419 XM_006717376 XP_006717439 XM_011519301 XP_011517603 XM_011519302 XP_011517604 NM_001202464 NP_001189393 NM_001202465 NP_001189394 NM_001202466 NP_001189395 NM_001202467 NP_001189396 NM_001202468 NP_001189397 NM_006624 NP_006615 NM_212479 NP_997644
Function Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth. {ECO:0000250|UniProtKB:Q8R5C8, ECO:0000269|PubMed:10734313, ECO:0000269|PubMed:16565076}.
Subcellular Location Nucleus. Chromosome. Note=Associates with chromatin and mitotic chromosomes.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:16565076}.

BS69 (E-20) - sc-15455 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

BS69 (F-14) - sc-15456 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BS69 (F-14): sc-15456. Western blot analysis of BS69 expression in mouse liver tissue extract.

BS69 (H-265) - sc-292571 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BS69 (H-265): sc-292571. Western blot analysis of BS69 expression in HeLa (A), RT-4 (B) and NIH/3T3 (C) whole cell lysates, mouse liver tissue extract (D) and Hep G2 nuclear extract (E).

Anti-BS69 antibody - ab14747 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-BS69 antibody - ab56025 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BS69 antibody (ab56025) at 1.25 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-BS69 antibody - ab168929 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-BS69 antibody (ab168929) at 1/500 dilutionLane 1 : BS69-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-BS69 antibody - N-terminal - ab135698 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-BS69 antibody - N-terminal (ab135698) at 1/100 dilution + Mouse brain tissue lysate at 35 µg

Anti-ZMYND11 / BS69 Antibody (aa42-53) - LS-C54596 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ZMYND11 / BS69 Antibody (aa111-160) - LS-C119055 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma tissue, using ZMY11 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-ZMYND11 / BS69 Antibody (aa138-187) - LS-C31796 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ZMYND11 / BS69 antibody LS-C31796 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-ZMYND11 / BS69 Antibody - LS-C334642 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using ZMYND11 antibody.

Anti-ZMYND11 / BS69 Antibody (aa119-148) - LS-C160801 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of ZMYND11 Antibody in mouse brain tissue lysates (35 ug/lane). ZMYND11 (arrow) was detected using the purified antibody.

Anti-ZMYND11 / BS69 Antibody (C-Terminus) - LS-C80102 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ZMYND11 / BS69 antibody LS-C80102 was used in IHC to stain formalin-fixed, paraffin-embedded human spleen.

ZMYND11 Antibody - NBP2-20960 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZMYND11 Antibody [NBP2-20960] - Western Blot analysis of ZMYND11 expression in transfected 293T cell line by ZMYND11 polyclonal antibody. A: Non-transfected lysate. B: ZMYND11 transfected lysate. 7. 5% SDS PAGE gel, diluted at 1:1000.

Adenovirus 5 E1A binding protein Antibody - bs-7697R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Formalin-fixed and paraffin embedded rat brain labeled with Anti-BS69/Adenovirus 5 E1A binding protein Polyclonal Antibody, Unconjugated (bs-7697R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Anti-ZMYND11 (N-terminal) antibody produced in goat - SAB2501744 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ZMyND11 (AB2) antibody produced in rabbit - AV34705 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZMYND11 (ab2): <B>Cat. No. AV34705</B>: Immunohistochemistry of ZMYND11 in Human Kidney tissue with ZMYND11 antibody at 4-8 μg/mL.

Anti-ZMY11 antibody produced in rabbit - SAB4500157 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZMY11: <B>Cat. No. SAB4500157</B>: Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Anti-ZMY11 antibody. Cells on the left were treated with the Anti-ZMY11 antibody. Cells on the right (negative control) were treated with both Anti-ZMY11 antibody and the synthesized immunogen peptide.

Anti-ZMyND11 (AB1) antibody produced in rabbit - AV34704 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-ZMYND11 (ab1): <B>Cat. No. AV34704</B>: Immunohistochemistry of ZMYND11 in Human Spleen tissue with ZMYND11 antibody at 4-8 μg/mL.

ZMYND11 antibody - middle region (ARP34704_T100) - ARP34704_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZMYND11 antibody - N-terminal region (ARP34705_T100) - ARP34705_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZMYND11-Antibody-N-term - AP8592a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of ZMYND11 Antibody (N-term) (Cat. #AP8592a) in mouse brain tissue lysates (35ug/lane). ZMYND11 (arrow) was detected using the purified Pab.

BS69--ZMYND11-Antibody-N-Term - AF2308a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

ZMYND11 Antibody - N-terminal region (OAAB05185) - OAAB05185 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

BS69 antibody, N-term - GTX14747 from GeneTex

Prices $289.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
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