| Gene Symbol |
TTLL11
|
| Entrez Gene |
158135
|
| Alt Symbol |
C9orf20, bA244O19.1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tubulin tyrosine ligase-like family member 11
|
| Other Description |
tubulin polyglutamylase TTLL11|tubulin tyrosine ligase-like family, member 11|tubulin--tyrosine ligase-like protein 11
|
| Swissprots |
Q8NHH1
|
| Accessions |
EAW87505 EAW87506 EAW87507 EAW87508 EAW87509 Q8NHH1 AF521886 AAM81328 AF521887 AAM81329 AK055126 AK123875 AK125178 BAC86073 BC040664 BC089452 BC169335 BC169336 BC171751 CV357789 HG502398 XM_005251728 XP_005251785 XM_005251729 XP_005251786 XM_006716966 XP_006717029 XR_929720 XR_929721 NM_001139442 NP_001132914 NM_194252 NP_919228
|
| Function |
Polyglutamase which preferentially modifies alpha- tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. {ECO:0000250, ECO:0000269|PubMed:22493317}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}.
|