Gene Symbol | TTLL11 |
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Entrez Gene | 158135 |
Alt Symbol | C9orf20, bA244O19.1 |
Species | Human |
Gene Type | protein-coding |
Description | tubulin tyrosine ligase-like family member 11 |
Other Description | tubulin polyglutamylase TTLL11|tubulin tyrosine ligase-like family, member 11|tubulin--tyrosine ligase-like protein 11 |
Swissprots | Q8NHH1 |
Accessions | EAW87505 EAW87506 EAW87507 EAW87508 EAW87509 Q8NHH1 AF521886 AAM81328 AF521887 AAM81329 AK055126 AK123875 AK125178 BAC86073 BC040664 BC089452 BC169335 BC169336 BC171751 CV357789 HG502398 XM_005251728 XP_005251785 XM_005251729 XP_005251786 XM_006716966 XP_006717029 XR_929720 XR_929721 NM_001139442 NP_001132914 NM_194252 NP_919228 |
Function | Polyglutamase which preferentially modifies alpha- tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. {ECO:0000250, ECO:0000269|PubMed:22493317}. |
Subcellular Location | Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. |
TTLL11 CRISPR/Cas9 KO Plasmid (h) - sc-414783 from Santa Cruz Biotechnology
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TTLL11 HDR Plasmid (h) - sc-414783-HDR from Santa Cruz Biotechnology
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TTLL11 Double Nickase Plasmid (h) - sc-414783-NIC from Santa Cruz Biotechnology
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TTLL11 Double Nickase Plasmid (h2) - sc-414783-NIC-2 from Santa Cruz Biotechnology
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TTLL11 CRISPR Activation Plasmid (h) - sc-414783-ACT from Santa Cruz Biotechnology
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TTLL11 CRISPR Activation Plasmid (h2) - sc-414783-ACT-2 from Santa Cruz Biotechnology
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TTLL11 Lentiviral Activation Particles (h) - sc-414783-LAC from Santa Cruz Biotechnology
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TTLL11 Lentiviral Activation Particles (h2) - sc-414783-LAC-2 from Santa Cruz Biotechnology
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TTLL11 siRNA (h) - sc-92676 from Santa Cruz Biotechnology
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TTLL11 shRNA Plasmid (h) - sc-92676-SH from Santa Cruz Biotechnology
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TTLL11 shRNA (h) Lentiviral Particles - sc-92676-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22197 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22197 from Sigma-Aldrich
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TTLL11 siRNA (Human) - CRJ5851 from Cohesion Biosciences
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TTLL11 - MBS8225129 from MyBioSource
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shRNA set against Human TTLL11 (NM_194252.2) - SHH437352 from Creative biogene
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Human TTLL11 siRNA - orb276352 from Biorbyt
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TTLL11 shRNA Plasmid (Human) - CHJ5851 from Cohesion Biosciences
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TTLL11 miRNA 3'UTR clone - MiUTR1H-10862 from Creative biogene
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TTLL11 miRNA 3'UTR clone - MiUTR3H-16463 from Creative biogene
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